Pamela R. Westmark

Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.

Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.

Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.

Seizure susceptibility and mortality in mice that over-express amyloid precursor protein.

MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta.

Pin1 and PKMzeta sequentially control dendritic protein synthesis.

Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures.

Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.