Department of Medicine
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Tamm-Horsfall Protein Translocates to the Basolateral Domain of Thick Ascending Limbs, Interstitium and Circulation during Recovery from Acute Kidney Injury.
American journal of physiology. Renal physiology Feb, 2013 | Pubmed ID: 23389456
An intricate network of conserved DNA upstream motifs and associated transcription factors regulate the expression of uromodulin gene.
The Journal of urology Sep, 2014 | Pubmed ID: 24594405
The role of tumor necrosis factor alpha in regulating the expression of Tamm-Horsfall Protein (uromodulin) in thick ascending limbs during kidney injury.
American journal of nephrology , 2014 | Pubmed ID: 25503683
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN Sep, 2015 | Pubmed ID: 25556169
Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis.
Physiological reports Feb, 2015 | Pubmed ID: 25677553
Tubular cross talk in acute kidney injury: a story of sense and sensibility.
American journal of physiology. Renal physiology Jun, 2015 | Pubmed ID: 25877507
Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells.
Journal of the American Society of Nephrology : JASN Jul, 2017 | Pubmed ID: 28154201
Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications.
Translational research : the journal of laboratory and clinical medicine Nov, 2017 | Pubmed ID: 28784428
Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia.
PloS one , 2017 | Pubmed ID: 29145399
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.
Journal of the American Society of Nephrology : JASN 03, 2018 | Pubmed ID: 29180395
Tamm-Horsfall protein/uromodulin deficiency elicits tubular compensatory responses leading to hypertension and hyperuricemia.
American journal of physiology. Renal physiology 06, 2018 | Pubmed ID: 29357410
siRNA Delivery and Rebound of Renal in Mice.
Journal of drug delivery , 2017 | Pubmed ID: 29410918
Quantitative Large-Scale Three-Dimensional Imaging of Human Kidney Biopsies: A Bridge to Precision Medicine in Kidney Disease.
Nephron , 2018 | Pubmed ID: 29870980
Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 01, 2020 | Pubmed ID: 30649494
Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study.
American journal of physiology. Gastrointestinal and liver physiology 10, 2019 | Pubmed ID: 31411505
Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis.
Clinical and translational gastroenterology 09, 2019 | Pubmed ID: 31478958
Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.
Science translational medicine Oct, 2019 | Pubmed ID: 31578243
Kidney Histopathology and Prediction of Kidney Failure: A Retrospective Cohort Study.
American journal of kidney diseases : the official journal of the National Kidney Foundation Apr, 2020 | Pubmed ID: 32336487
Hospital-Acquired Versus Community-Acquired Acute Kidney Injury in Patients With Cirrhosis: A Prospective Study.
The American journal of gastroenterology May, 2020 | Pubmed ID: 32371628
A Precision Medicine Approach Uncovers a Unique Signature of Neutrophils in Patients With Brushite Kidney Stones.
Kidney international reports May, 2020 | Pubmed ID: 32405588
Daria Barwinska1,
Michael J. Ferkowicz1,
Ying-Hua Cheng1,
Seth Winfree1,2,
Kenneth W. Dunn1,
Katherine J. Kelly1,
Timothy A. Sutton1,
Brad H. Rovin3,
Samir V. Parikh3,
Carrie L. Phillips4,
Pierre C. Dagher1,
Tarek M. El-Achkar1,
Michael T. Eadon1,
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1Department of Medicine, Indiana University School of Medicine,
2Department of Cellular & Integrative Physiology, Indiana University School of Medicine,
3Division of Nephrology, Department of Medicine, Ohio State University Wexner Medical Center,
4Division of Pathology, Indiana University School of Medicine
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