Department of Pathology and Cell Biology
Lloyd A. Greene has not added Biography.
If you are Lloyd A. Greene and would like to personalize this page please email our Author Liaison for assistance.
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins.
BMC neuroscience , 2002 | Pubmed ID: 11922865
Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12388545
The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2002 | Pubmed ID: 12388604
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2002 | Pubmed ID: 12486162
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.
The EMBO journal Jan, 2003 | Pubmed ID: 12514131
Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2003 | Pubmed ID: 12805299
Malignant pheochromocytoma: current status and initiatives for future progress.
Endocrine-related cancer Sep, 2004 | Pubmed ID: 15369446
B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2004 | Pubmed ID: 15470138
Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15537872
Analysis of gene expression changes in a cellular model of Parkinson disease.
Neurobiology of disease Feb, 2005 | Pubmed ID: 15649696
Regulation of neuron survival and death by p130 and associated chromatin modifiers.
Genes & development Mar, 2005 | Pubmed ID: 15769944
Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2005 | Pubmed ID: 15829641
ATF5 regulates the proliferation and differentiation of oligodendrocytes.
Molecular and cellular neurosciences Jul, 2005 | Pubmed ID: 15950153
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism.
Journal of neurochemistry Nov, 2005 | Pubmed ID: 16135078
Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2005 | Pubmed ID: 16162916
Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease.
Neurochemical research Jun-Jul, 2005 | Pubmed ID: 16187218
Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.
The Journal of biological chemistry Jan, 2006 | Pubmed ID: 16230351
Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.
Molecular and cellular biology Nov, 2005 | Pubmed ID: 16260609
You can't go home again: transcriptionally driven alteration of cell signaling by NGF.
Neurochemical research Oct, 2005 | Pubmed ID: 16341597
Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH.
Methods in enzymology , 2006 | Pubmed ID: 16472680
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.
The Journal of biological chemistry Jun, 2006 | Pubmed ID: 16571722
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2006 | Pubmed ID: 17005863
Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model.
The Journal of biological chemistry Jan, 2007 | Pubmed ID: 17095503
Cell cycle molecules define a pathway required for neuron death in development and disease.
Biochimica et biophysica acta Apr, 2007 | Pubmed ID: 17229557
Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2007 | Pubmed ID: 17251431
The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines.
International journal of cancer. Journal international du cancer May, 2007 | Pubmed ID: 17266024
Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways.
The Journal of biological chemistry Oct, 2007 | Pubmed ID: 17702754
Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH.
Developmental neuroscience , 2007 | Pubmed ID: 17762203
Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction.
Neurochemical research Sep, 2008 | Pubmed ID: 18351462
The transcription factor ATF5: role in neurodevelopment and neural tumors.
Journal of neurochemistry Jan, 2009 | Pubmed ID: 19046351
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2008 | Pubmed ID: 19118169
Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.
Apoptosis : an international journal on programmed cell death Apr, 2009 | Pubmed ID: 19165601
Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells.
Molecular cancer research : MCR Jun, 2009 | Pubmed ID: 19531563
Cbl negatively regulates JNK activation and cell death.
Cell research Aug, 2009 | Pubmed ID: 19546888
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2010 | Pubmed ID: 20089925
Sertad1 plays an essential role in developmental and pathological neuron death.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2010 | Pubmed ID: 20237268
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2011 | Pubmed ID: 21368030
Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2011 | Pubmed ID: 21430145
Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment.
Cellular and molecular neurobiology Oct, 2011 | Pubmed ID: 21547489
Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells.
Developmental neurobiology Sep, 2011 | Pubmed ID: 22095825
Sh3rf2/POSHER Protein Promotes Cell Survival by Ring-mediated Proteasomal Degradation of the c-Jun N-terminal Kinase Scaffold POSH (Plenty of SH3s) Protein.
The Journal of biological chemistry Jan, 2012 | Pubmed ID: 22128169
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados