Acupuncture in a Rat Model of Asthma

A high platform can fix rats without restriction and completely expose the acupoints on the back during acupuncture manipulation. This article describes ...

Shanghai University of Traditional Chinese Medicine

Acupuncture has long been used for asthma treatment but the underlying mechanism remains unclear. Previous study showed that metallothionein-2 (MT-2) was significantly decreased in asthmatic lung tissue. However, the relationship between acupuncture treatment and MT-2 expression during asthma is still unknown, and the detailed effect analysis of MT-2 on phosphorylation in airway smooth muscle cells (ASMCs) is also unclear.

Metallothionein-2 is associated with the amelioration of asthmatic pulmonary function by acupuncture through protein phosphorylation.

Standard therapy for asthma, a highly heterogeneous disease, is primarily based on bronchodilators and immunosuppressive drugs, which confer short-term symptomatic relief but not a cure. It is difficult to discover novel bronchodilators, although potential new targets are emerging. Traditional Chinese Medicine (TCM) formulas have been used to treat asthma for more than 2000 years, forming the basis for representative asthma treatments.

Dong-Dong Zhou

Laboratory of Molecular Biology,
Shanghai Research Institute of Acupuncture and Meridian,
Laboratory of Molecular Biology, Shanghai Research Institute of Acupuncture and Meridian

Shanghai University of Traditional Chinese Medicine

Acupuncture in a Rat Model of Asthma

Dong-Dong Zhou

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Laboratory of Molecular Biology,Shanghai Research Institute of Acupuncture and Meridian,Laboratory of Molecular Biology, Shanghai Research Institute of Acupuncture and Meridian

Shanghai University of Traditional Chinese Medicine

Acupuncture in a Rat Model of Asthma

Laboratory of Molecular Biology,
Shanghai Research Institute of Acupuncture and Meridian,
Laboratory of Molecular Biology, Shanghai Research Institute of Acupuncture and Meridian