Magdalena M. Szewczyk

A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).

Discovery of a Dual PRMT5-PRMT7 Inhibitor.

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.

Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors.

Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3).

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma.

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.

Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression.

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.

Discovery of a chemical probe for PRDM9.

Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.

Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders.

Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid.