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Department of Neuroscience Care and Society,
Division of Neurogeriatrics,
Department of Neuroscience Care and Society, Division of Neurogeriatrics
Rajnish Kumar has not added Biography.
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Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs.
Brain : a journal of neurology Jan, 2016 | Pubmed ID: 26525916
Novel ligands of Choline Acetyltransferase designed by in silico molecular docking, hologram QSAR and lead optimization.
Scientific reports 08, 2016 | Pubmed ID: 27507101
Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.
Scientific reports 10, 2017 | Pubmed ID: 29079741
Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening.
Scientific reports 11, 2017 | Pubmed ID: 29176551
Synthesis, crystal structure and antimicrobial potential of some fluorinated chalcone-1,2,3-triazole conjugates.
European journal of medicinal chemistry Jul, 2018 | Pubmed ID: 29890388
Soluble Aβ42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 30271321
identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network.
FEBS open bio Nov, 2018 | Pubmed ID: 30410862
Metal Binding by GMP-1 and Its Pyrimido [1, 2]benzimidazole Analogs Confirms Protection Against Amyloid-β Associated Neurotoxicity.
Journal of Alzheimer's disease : JAD , 2020 | Pubmed ID: 31839606
Proton pump inhibitors act with unprecedented potencies as inhibitors of the acetylcholine biosynthesizing enzyme-A plausible missing link for their association with incidence of dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association 07, 2020 | Pubmed ID: 32383816
Esomeprazole reduces sperm motility index by targeting the spermic cholinergic machinery: A mechanistic study for the association between use of proton pump inhibitors and reduced sperm motility index.
Biochemical pharmacology 12, 2020 | Pubmed ID: 32866455
Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance.
European journal of medicinal chemistry Jan, 2021 | Pubmed ID: 33139110
Karolinska Institutet
Indian Institute of Technology (BHU)
Lisha Wang1,
Liza Bergkvist1,
Rajnish Kumar1,2,
Bengt Winblad1,3,
Pavel F. Pavlov1
1Department of Neuroscience Care and Society, Division of Neurogeriatrics, Karolinska Institutet,
2Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (BHU),
3Theme Inflammation and Aging, Karolinska University Hospital
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