Life Science Center for Survival Dynamics,
Tsukuba Advanced Research Alliance (TARA),
Faculty of Medicine,
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
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Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.
Matrix biology : journal of the International Society for Matrix Biology 12, 2018 | Pubmed ID: 29730503
Differences in genetic signaling, and not mechanical properties of the wall, are linked to ascending aortic aneurysms in fibulin-4 knockout mice.
American journal of physiology. Heart and circulatory physiology Jul, 2015 | Pubmed ID: 25934097
MMP17/MT4-MMP and thoracic aortic aneurysms: OPNing new potential for effective treatment.
Circulation research Jul, 2015 | Pubmed ID: 26139854
Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations.
Human molecular genetics Oct, 2015 | Pubmed ID: 26220971
Molecular basis of cleft palates in mice.
World journal of biological chemistry Aug, 2015 | Pubmed ID: 26322171
Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice.
Science signaling Oct, 2015 | Pubmed ID: 26486174
Specification of jaw identity by the Hand2 transcription factor.
Scientific reports 06, 2016 | Pubmed ID: 27329940
Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets.
Scientific reports 05, 2017 | Pubmed ID: 28539593
Crosslinked elastic fibers are necessary for low energy loss in the ascending aorta.
Journal of biomechanics 08, 2017 | Pubmed ID: 28778385
Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1.
Circulation Sep, 2017 | Pubmed ID: 28778947
Crossing Bridges between Extra- and Intra-Cellular Events in Thoracic Aortic Aneurysms.
Journal of atherosclerosis and thrombosis Feb, 2018 | Pubmed ID: 28943527
Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer.
Oncotarget Mar, 2018 | Pubmed ID: 29581841
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
Cardiovascular research 11, 2018 | Pubmed ID: 29931197
Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.
Archives of oral biology Nov, 2018 | Pubmed ID: 30121012
Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans.
Circulation research 08, 2018 | Pubmed ID: 30355232
Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.
Cellular signalling 06, 2019 | Pubmed ID: 30844428
Elastic fibers and biomechanics of the aorta: Insights from mouse studies.
Matrix biology : journal of the International Society for Matrix Biology 01, 2020 | Pubmed ID: 30880160
Wild-type and SAMP8 mice show age-dependent changes in distinct stem cell compartments of the interfollicular epidermis.
PloS one , 2019 | Pubmed ID: 31091266
Recent updates on the molecular network of elastic fiber formation.
Essays in biochemistry 09, 2019 | Pubmed ID: 31395654
Fibulin-4 exerts a dual role in LTBP-4L-mediated matrix assembly and function.
Proceedings of the National Academy of Sciences of the United States of America 10, 2019 | Pubmed ID: 31548410
Novel ELN mutation in a Japanese family with a severe form of supravalvular aortic stenosis.
Molecular genetics & genomic medicine 11, 2019 | Pubmed ID: 31560829
Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling.
Proceedings of the National Academy of Sciences of the United States of America 05, 2020 | Pubmed ID: 32321834
Role of PAR1-Egr1 in the Initiation of Thoracic Aortic Aneurysm in Fbln4-Deficient Mice.
Arteriosclerosis, thrombosis, and vascular biology 08, 2020 | Pubmed ID: 32580633
Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging.
Aging cell 08, 2020 | Pubmed ID: 32681764
The molecular mechanism of mechanotransduction in vascular homeostasis and disease.
Clinical science (London, England : 1979) 09, 2020 | Pubmed ID: 32936305
Dysregulated assembly of elastic fibers in fibulin-5 knockout mice results in a tendon-specific increase in elastic modulus.
Journal of the mechanical behavior of biomedical materials 01, 2021 | Pubmed ID: 33045519
Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium.
Development (Cambridge, England) 12, 2020 | Pubmed ID: 33199446
Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels.
Scientific reports Apr, 2021 | Pubmed ID: 33883668
Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms.
Cell reports. Medicine May, 2021 | Pubmed ID: 34095874
Extracellular matrix-mediated remodeling and mechanotransduction in large vessels during development and disease.
Cellular signalling Oct, 2021 | Pubmed ID: 34339854
Yen Xuan Ngo1,2,3,
Kenta Haga4,
Ayako Suzuki4,
Hiroko Kato4,
Hiromi Yanagisawa1,5,
Kenji Izumi4,
Aiko Sada1,3
1Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba,
2Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba,
3International Research Center for Medical Sciences (IRCMS), Kumamoto University,
4Division of Biomimetics, Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Niigata University,
5Faculty of Medicine, University of Tsukuba
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