John P. Kirwan

Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes.

Mechanisms Responsible for Metabolic Improvements of Bariatric Surgeries.

Mitochondrial dynamics in skeletal muscle insulin resistance and type 2 diabetes.

Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype.

Exercise-induced improvements in glucose effectiveness are blunted by a high glycemic diet in adults with prediabetes.

Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults.

The historical context and scientific legacy of John O. Holloszy.

Medical marijuana-an obesity problem or opportunity?

A Whole-Grain Diet Increases Glucose-Stimulated Insulin Secretion Independent of Gut Hormones in Adults at Risk for Type 2 Diabetes.

Gastric Bypass Surgery Improves the Skeletal Muscle Ceramide/S1P Ratio and Upregulates the AMPK/ SIRT1/ PGC-1α Pathway in Zucker Diabetic Fatty Rats.

Exercise training promotes a GDF15-associated reduction in fat mass in older adults with obesity.

Skeletal muscle Nur77 and NOR1 insulin responsiveness is blunted in obesity and type 2 diabetes but improved after exercise training.

Exercise Mitigates Bone Loss in Women With Severe Obesity After Roux-en-Y Gastric Bypass: A Randomized Controlled Trial.

Non-invasive assessment of hepatic lipid subspecies matched with non-alcoholic fatty liver disease phenotype.

UCC118 supplementation reduces exercise-induced gastrointestinal permeability and remodels the gut microbiome in healthy humans.

Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD.

A randomized controlled trial to reduce sedentary time in rheumatoid arthritis: protocol and rationale of the Take a STAND for Health study.

Lipids and ketones dominate metabolism at the expense of glucose control in pulmonary arterial hypertension: a hyperglycaemic clamp and metabolomics study.

Plasma metabolomic profile in chronic thromboembolic pulmonary hypertension.

Joint international consensus statement for ending stigma of obesity.

Rationale and study design for lifestyle intervention in preparation for pregnancy (LIPP): A randomized controlled trial.

β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro.

Exercise-Induced Increases in Insulin Sensitivity After Bariatric Surgery Are Mediated By Muscle Extracellular Matrix Remodeling.

Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes.

Effects of gastric bypass surgery on expression of glucose transporters and fibrotic biomarkers in kidney of diabetic fatty rats.

BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control.

Exercise plus caloric restriction lowers soluble RAGE in adults with chronic kidney disease.

Metabolic effects of duodenojejunal bypass surgery in a rat model of type 1 diabetes.

Mitochondrial Utilization of Competing Fuels Is Altered in Insulin Resistant Skeletal Muscle of Non-obese Rats (Goto-Kakizaki).

Obesity, the most common comorbidity in SARS-CoV-2: is leptin the link?

Adiposity, Physical Function, and Their Associations With Insulin Resistance, Inflammation, and Adipokines in CKD.

Outpatient Screening of Health Status Among Postbariatric Patients during the COVID-19 Pandemic in Sao Paulo, Brazil.

Exercise Enhances the Effect of Bariatric Surgery in Markers of Cardiac Autonomic Function.

Sleep Extension: A Potential Target for Obesity Treatment.

Roux-en-Y Gastric Bypass Restores Islet Function and Morphology Independent of Body Weight in ZDF Rats.

Resting Energy Expenditure Is Elevated in Asthma.

Foregut Exclusion Enhances Incretin and Insulin Secretion After Roux-en-Y Gastric Bypass in Adults with Type 2 Diabetes.

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans.

Exercise Is Key to Sustaining Metabolic Gains After Bariatric Surgery.

Patient Reported Outcomes after Metabolic Surgery Versus Medical Therapy for Diabetes: Insights from the STAMPEDE Randomized Trial.

CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases.

Constraints of Weight Loss as a Marker of Bariatric Surgery Success: An Exploratory Study.

CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases.