Yuan-Hao Hsu

Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.

A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2.

Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange.

2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.

Localizing the membrane binding region of Group VIA Ca2+-independent phospholipase A2 using peptide amide hydrogen/deuterium exchange mass spectrometry.

Reciprocally coupled residues crucial for protein kinase Pak2 activity calculated by statistical coupling analysis.

Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.

Lipoprotein-associated phospholipase A(2) interacts with phospholipid vesicles via a surface-disposed hydrophobic α-helix.

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.

Essential role of ELOVL4 in very long chain fatty acid synthesis and retinal function.