Christian Lehmann

Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia.

Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats.

Fructose--the sweet poison.

Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis.

Activated protein C improves pial microcirculation in experimental endotoxemia in rats.

Microcirculation diagnostics and applied studies in circulatory shock - research from the bench to the bedside.

Cannabinoid receptor 1 inhibition improves the intestinal microcirculation in experimental endotoxemia.

Inhibition of endocannabinoid degradation in experimental endotoxemia reduces leukocyte adhesion and improves capillary perfusion in the gut.

Physostigmine reverses disturbances of the intestinal microcirculation during experimental endotoxemia.

Oxidized LDL and LOX-1 in experimental sepsis.

Comparison of cold crystalloid and colloid infusions for induction of therapeutic hypothermia in a porcine model of cardiac arrest.

The last bite was deadly--about responsibility in scientific publishing.

Effect of deletion of cIAP2 on intestinal microcirculation in mouse endotoxemia and polybacterial sepsis.

Novel approaches to the development of anti-sepsis drugs.

Inhibition of the cannabinoid 2 receptor in CNS-injury induced immunodeficiency syndrome.

Unanticipated expanding neck mass under general anesthesia.

Adenosine receptor activation improves microcirculation in experimental intestinal ischemia/reperfusion.

Combination of dehydroepiandrosterone and orthovanadate administration reduces intestinal leukocyte recruitment in models of experimental sepsis.

Short time impact of different hydroxyethyl starch solutions on the mesenteric microcirculation in experimental sepsis in rats.

Impact of methylene blue in addition to norepinephrine on the intestinal microcirculation in experimental septic shock.

New directions for sepsis and septic shock research.

Evaluation of the effects of Eserine and JWH-133 on brain dysfunction associated with experimental endotoxemia.

Experimental TLR4 inhibition improves intestinal microcirculation in endotoxemic rats.

Sidestream versus incident dark field imaging: How to compare two different technologies to study the microcirculation?

Anti-inflammatory and anti-bacterial effects of iron chelation in experimental sepsis.

Analysis of microcirculation measurements by novice users trained by a standardized interactive tutorial: An inter-observer variability study.

Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial.

Therapeutic iron restriction in sepsis.

Experimental Cannabinoid 2 Receptor Inhibition in CNS Injury-Induced Immunodeficiency Syndrome.

Effects of haemoglobin levels on the sublingual microcirculation in pregnant women.

Cannabinoid 2 receptor is a novel anti-inflammatory target in experimental proliferative vitreoretinopathy.

CB2 and GPR55 Receptors as Therapeutic Targets for Systemic Immune Dysregulation.

Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.

An intravital microscopy model to study early pancreatic inflammation in type 1 diabetes in NOD mice.

Iron chelation for the treatment of uveitis.

Tetrahydrobiopterin improves microcirculation in experimental sepsis.

A.L. Copley Best Paper Prize 2016.

Iron chelation as novel treatment for lung inflammation in cystic fibrosis.

Anti-inflammatory effects of a novel iron chelator, DIBI, in experimental sepsis.

New developments in clinical microcirculation imaging.

Preliminary clinical evaluation of automated analysis of the sublingual microcirculation in the assessment of patients with septic shock: Comparison of automated versus semi-automated software.

Microcirculation research in community hospitals - challenges and chances.

Glycocalyx in vivo measurement.

Immune response to systemic inflammation in the intestinal microcirculation.

Targeting the endothelial glycocalyx in acute critical illness as a challenge for clinical and laboratory medicine.

Clinical relevance of early sublingual microcirculation monitoring in septic shock patients.

Parameters of the Endocannabinoid System as Novel Biomarkers in Sepsis and Septic Shock.

Betacaryophyllene - A phytocannabinoid as potential therapeutic modality for human sepsis?

Sidestream Dark Field Imaging of the Microcirculation to Assess Preeclampsia Microvascular Dysfunction.

A.L. Copley Best Paper Prize 2017.

Impact of insulin on the intestinal microcirculation in a model of sepsis-related hyperglycemia.

Impact of lipid modulation on the intestinal microcirculation in experimental sepsis.

The Ongoing Challenge of Acute Mesenteric Ischemia.

Selective sensitivity of the gut microbiome to iron chelators in polybacterial abdominal sepsis.

Rapid clinical assessment of the sublingual microcirculation - Visual scoring using microVAS in comparison to standard semi-automated analysis.

Clinical assessment of arthritic knee pain by infrared thermography.

Effect of acute hypernatremia induced by hypertonic saline administration on endothelial glycocalyx in rabbits.

Neuraxial anesthesia is less harmful to the endothelial glycocalyx during elective joint surgery compared to general anesthesia.

Impact of Intravenous Fluid Challenge Infusion Time on Macrocirculation and Endothelial Glycocalyx in Surgical and Critically Ill Patients.

Laser Doppler-based measurements of periarticular blood flux can be utilized for assessment of arthritis pain: A hypothesis.

Modulation of the Endocannabinoid System Following Central Nervous System Injury.

Iron Chelation as Novel Treatment for Interstitial Cystitis.

ATP in red blood cells as biomarker for sepsis in humans.

Bacterial Resistance in Pneumonia in Developing Countries-A Role for Iron Chelation.

Challenges for microcirculation research in developing countries.

Effect of short-term administration of lipid emulsion on endothelial glycocalyx integrity in ICU patients - A microvascular and biochemical pilot study.

A.L. Copley Best Paper Prize 2018.

Possible Impact of Spinal Anesthesia and Phenylephrine on Sublingual Microcirculation of Cesarean Delivery Patients.

Monoacylglycerol lipase inhibition as potential treatment for interstitial cystitis.

Inflammatory Response to Different Toxins in Experimental Sepsis Models.

Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis.

Iron should be restricted in acute infection.

Microcirculatory Changes in Experimental Models of Stroke and CNS-Injury Induced Immunodepression.

Evaluation of endothelial glycocalyx in healthy volunteers - An observational study.

Experimental Cannabinoid 2 Receptor Activation by Phyto-Derived and Synthetic Cannabinoid Ligands in LPS-Induced Interstitial Cystitis in Mice.

The curative effect of a cannabinoid 2 receptor agonist on functional failure and disruptive inflammation caused by intestinal ischemia and reperfusion.

Endothelial glycocalyx in acute care surgery - what anaesthesiologists need to know for clinical practice.

Molecular mechanisms by which iNOS uncoupling can induce cardiovascular dysfunction during sepsis: Role of posttranslational modifications (PTMs).

Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins.

A.L. Copley Best Paper Prize 2019.

Personal protective equipment during the COVID-19 pandemic (Letter #2).

The novel iron chelator, DIBI, attenuates inflammation and improves outcome in colon ascendens stent peritonitis-induced experimental sepsis.

Imaging of the Intestinal Microcirculation during Acute and Chronic Inflammation.

Iron Chelation in Local Infection.

Comparison of Treatment Effects of Different Iron Chelators in Experimental Models of Sepsis.

Intravital Imaging of Pulmonary Immune Response in Inflammation and Infection.

Cannabinoid Receptor 1 and 2 Signaling Pathways Involved in Sepsis.

A.L. Copley Best Paper Prize 2020.

National Preclinical Sepsis Platform: developing a framework for accelerating innovation in Canadian sepsis research.

A porcine model of endothelial glycocalyx damage by enzymatic digestion: A pilot study.

Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles' heel of antibiotic-resistant microbes.

Effect of Cannabinoid 2 Receptor Modulation on the Peripheral Immune Response in Central Nervous System Injury-Induced Immunodeficiency Syndrome.

Real-Time Imaging of Immune Modulation by Cannabinoids Using Intravital Fluorescence Microscopy.

Sensitivity Patterns of Bacterial Pathogens Isolated from Blood Cultures of Under-Five Children with Pneumonia and Clinical Sepsis.

Effects of CNS Injury-Induced Immunosuppression on Pulmonary Immunity.

Anti-inflammatory iron chelator, DIBI, reduces leukocyte-endothelial adhesion and clinical symptoms of LPS-induced interstitial cystitis in mice.

Rodent models of ketamine-induced cystitis.

Utility of intestinal intravital microscopy for the study of CNS injury-induced immunodepression syndrome (CIDS).

Clinical features of pneumonia in severely malnourished children with diarrhoea compared to those without diarrhoea.

Components of the Endogenous Cannabinoid System as Potential Biomarkers for Interstitial Cystitis/Bladder Pain Syndrome.

Endothelial glycocalyx damage in patients with severe COVID-19 on mechanical ventilation - a prospective observational pilot study.

Assessing the impact of predatory journals on policy and guidance documents: a cross-sectional study protocol.