Siiri E. Iismaa

Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases.

Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria.

Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity.

Cross-linking transglutaminases with G protein-coupled receptor signaling.

Mechanism of allosteric regulation of transglutaminase 2 by GTP.

Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders.

Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.

Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry.

Transglutaminase 2 and its role in pulmonary fibrosis.

Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.

Glucose homeostasis in mice is transglutaminase 2 independent.

A proliferative burst during preadolescence establishes the final cardiomyocyte number.

RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility.

Thyroid hormone action in postnatal heart development.

Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period.

Cardiomyocytes Replicate and their Numbers Increase in Young Hearts.

The prostate-specific protein, transglutaminase 4 (TG4), is an autoantigen associated with male subfertility.

Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice.

Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia.

Transglutaminase diseases: from biochemistry to the bedside.

Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.

Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection.

Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency.

Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice.

Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women.

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation.

Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes.

Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing.

DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling.

Adaptation to exercise-induced stress is not dependent on cardiomyocyte α-adrenergic receptors.

The Ca-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy.

Mechanism-Based Cardiac Regeneration Strategies in Mammals.

Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing.

Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts.