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Department of Genetics
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Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development.
Nature genetics Jun, 2002 | Pubmed ID: 12006978
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint.
Molecular cell May, 2002 | Pubmed ID: 12049741
Identification of 315 genes essential for early zebrafish development.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2004 | Pubmed ID: 15256591
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney.
Development (Cambridge, England) Aug, 2004 | Pubmed ID: 15269167
No age-related cell loss in three retinal nuclear layers of the Long-Evans rat.
Visual neuroscience Nov-Dec, 2007 | Pubmed ID: 18093367
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
Developmental cell Jun, 2008 | Pubmed ID: 18539122
Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway.
Human molecular genetics Feb, 2009 | Pubmed ID: 19008302
Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion.
Development (Cambridge, England) Dec, 2009 | Pubmed ID: 19906870
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2009 | Pubmed ID: 19966229
Intraflagellar transport proteins are essential for cilia formation and for planar cell polarity.
Journal of the American Society of Nephrology : JASN Aug, 2010 | Pubmed ID: 20576807
The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2010 | Pubmed ID: 20937855
Cilia in cell signaling and human disorders.
Protein & cell Aug, 2010 | Pubmed ID: 21203914
A cell-based screen for inhibitors of flagella-driven motility in Chlamydomonas reveals a novel modulator of ciliary length and retrograde actin flow.
Cytoskeleton (Hoboken, N.J.) Mar, 2011 | Pubmed ID: 21360831
Analysis of cilia structure and function in zebrafish.
Methods in cell biology , 2011 | Pubmed ID: 21550439
Qilin is essential for cilia assembly and normal kidney development in zebrafish.
PloS one , 2011 | Pubmed ID: 22102889
The γ-Secretase Cleavage Product of Polycystin-1 Regulates TCF and CHOP-Mediated Transcriptional Activation through a p300-Dependent Mechanism.
Developmental cell Jan, 2012 | Pubmed ID: 22178500
Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308353
Yale University School of Medicine
Shiaulou Yuan1,
Zhaoxia Sun1
1Department of Genetics, Yale University School of Medicine
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