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Ruchi Sharma

Ocular and Stem Cell Translational Research Section,
National Eye Institute,
Ocular and Stem Cell Translational Research Section, National Eye Institute

National Institutes of Health (NIH)

BIOGRAPHY

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PUBLICATIONS

In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications.

Stem cells translational medicine Jul, 2016 | Pubmed ID: 27400791

Polarized Human Retinal Pigment Epithelium Exhibits Distinct Surface Proteome on Apical and Basal Plasma Membranes.

Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29264809

Retinal Pigment Epithelium Replacement Therapy for Age-Related Macular Degeneration: Are We There Yet?

Annual review of pharmacology and toxicology 01, 2020 | Pubmed ID: 31914900

Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.

Nature communications Dec, 2021 | Pubmed ID: 34911940

In vitro disease modeling of oculocutaneous albinism type 1 and 2 using human induced pluripotent stem cell-derived retinal pigment epithelium.

Stem cell reports Jan, 2022 | Pubmed ID: 35021041

Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells.

STAR protocols Sep, 2022 | Pubmed ID: 35880133

Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells.

Stem cell reports Nov, 2022 | Pubmed ID: 36306781

Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.

Nature methods Jan, 2023 | Pubmed ID: 36550275

Portable Breath-Based Volatile Organic Compound Monitoring for the Detection of COVID-19 During the Circulation of the SARS-CoV-2 Delta Variant and the Transition to the SARS-CoV-2 Omicron Variant.

JAMA network open Feb, 2023 | Pubmed ID: 36853606

Considerations for Developing an Autologous Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Replacement Therapy.

Cold Spring Harbor perspectives in medicine Jul, 2023 | Pubmed ID: 37487631

INSTITUTIONS

National Institutes of Health (NIH)

JOVE ARTICLES

Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis

Davide Ortolan¹,

Andrei Volkov¹,

Arvydas Maminishkis¹,

Ruchi Sharma¹,

Kapil Bharti¹

¹Ocular and Stem Cell Translational Research Section, National Eye Institute, National Institutes of Health (NIH)

Biology

LipidUNet-Machine Learning-Based Method of Characterization and Quantification of Lipid Deposits Using iPSC-Derived Retinal Pigment Epithelium

Zander Esh^*,1,

Sharanya Suresh^*,1,

Davide Ortolan¹,

Mitra Farnoodian¹,

Devika Bose¹,

Jiwon Ryu¹,

Andrei Volkov¹,

Kapil Bharti¹,

Ruchi Sharma¹

¹Ocular and Stem Cell Translational Research Section, National Eye Institute, National Institutes of Health (NIH)

Biology

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Ruchi Sharma

Ocular and Stem Cell Translational Research Section,National Eye Institute,Ocular and Stem Cell Translational Research Section, National Eye Institute

National Institutes of Health (NIH)

Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis

LipidUNet-Machine Learning-Based Method of Characterization and Quantification of Lipid Deposits Using iPSC-Derived Retinal Pigment Epithelium

Ocular and Stem Cell Translational Research Section,
National Eye Institute,
Ocular and Stem Cell Translational Research Section, National Eye Institute