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Section for Immunology,
Joslin Diabetes Center,
Section for Immunology, Joslin Diabetes Center
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T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice.
The Journal of experimental medicine Jul, 2002 | Pubmed ID: 12093873
Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2004 | Pubmed ID: 14694195
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.
The Journal of clinical investigation Dec, 2010 | Pubmed ID: 21099114
PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant.
Diabetes Mar, 2013 | Pubmed ID: 23193190
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection.
Immunity May, 2015 | Pubmed ID: 25979422
Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2015 | Pubmed ID: 26404487
Ptpn22 Modifies Regulatory T Cell Homeostasis via GITR Upregulation.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2016 | Pubmed ID: 26810223
The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells.
Genes and immunity 06, 2016 | Pubmed ID: 27029527
In Vivo Enrichment of Diabetogenic T Cells.
Diabetes 08, 2017 | Pubmed ID: 28396510
Peripherally induced regulatory T cells contribute to the control of autoimmune diabetes in the NOD mouse model.
European journal of immunology 07, 2018 | Pubmed ID: 29604048
Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity.
Science signaling 06, 2018 | Pubmed ID: 29895617
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes.
Nature metabolism May, 2019 | Pubmed ID: 31423480
The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model.
Genes and immunity 01, 2020 | Pubmed ID: 31435002
Anti-CD3 Antibody for the Prevention of Type 1 Diabetes: A Story of Perseverance.
Biochemistry 10, 2019 | Pubmed ID: 31523950
Regulation of B cell homeostasis by Ptpn22 contributes to type 1 diabetes in NOD mice.
Endocrine 03, 2020 | Pubmed ID: 31732921
Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes.
Nature metabolism 09, 2020 | Pubmed ID: 32719542
Genetic Modifiers of Thymic Selection and Central Tolerance in Type 1 Diabetes.
Frontiers in immunology , 2022 | Pubmed ID: 35464420
Toward a precision medicine approach for autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America 05, 2022 | Pubmed ID: 35522710
CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells.
Frontiers in immunology , 2022 | Pubmed ID: 35720357
Harvard Medical School
Taylor Stewart1,
Kevin Bode2,
Stephan Kissler2,
Peng Yi1
1Section for Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School,
2Section for Immunology, Joslin Diabetes Center, Harvard Medical School
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