Department of Orthopaedic Surgery,
McGowan Institute for Regenerative Medicine
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Mesenchymal progenitor cells derived from traumatized muscle enhance neurite growth.
Journal of tissue engineering and regenerative medicine Jun, 2013 | Pubmed ID: 22552971
Application of visible light-based projection stereolithography for live cell-scaffold fabrication with designed architecture.
Biomaterials Jan, 2013 | Pubmed ID: 23092861
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix.
Biomaterials Dec, 2013 | Pubmed ID: 24044998
High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer.
BioTechniques , 2014 | Pubmed ID: 24502798
Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution.
Tissue engineering. Part A Sep, 2014 | Pubmed ID: 24575844
Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1β.
Molecular pharmaceutics Jul, 2014 | Pubmed ID: 24830762
Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases.
Experimental biology and medicine (Maywood, N.J.) Sep, 2014 | Pubmed ID: 24994814
Platelet-Rich Plasma Inhibits Mechanically Induced Injury in Chondrocytes.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association Jun, 2015 | Pubmed ID: 25769480
Development of a Spring-Loaded Impact Device to Deliver Injurious Mechanical Impacts to the Articular Cartilage Surface.
Cartilage Jan, 2013 | Pubmed ID: 26069650
Augmented repair of radial meniscus tear with biomimetic electrospun scaffold: an in vitro mechanical analysis.
Journal of experimental orthopaedics Dec, 2016 | Pubmed ID: 27624439
Prenatal exposure to environmental factors and congenital limb defects.
Birth defects research. Part C, Embryo today : reviews Sep, 2016 | Pubmed ID: 27768243
Anatomical region-dependent enhancement of 3-dimensional chondrogenic differentiation of human mesenchymal stem cells by soluble meniscus extracellular matrix.
Acta biomaterialia Feb, 2017 | Pubmed ID: 27876676
Neurotrophic support by traumatized muscle-derived multipotent progenitor cells: Role of endothelial cells and Vascular Endothelial Growth Factor-A.
Stem cell research & therapy Oct, 2017 | Pubmed ID: 29029631
Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology.
Stem cell research & therapy Apr, 2018 | Pubmed ID: 29678192
Effect of Platelet-Rich Plasma on Chondrogenic Differentiation of Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells.
Tissue engineering. Part A Oct, 2018 | Pubmed ID: 30036140
Enhancing chondrogenesis and mechanical strength retention in physiologically relevant hydrogels with incorporation of hyaluronic acid and direct loading of TGF-β.
Acta biomaterialia Jan, 2019 | Pubmed ID: 30458242
Conduits harnessing spatially controlled cell-secreted neurotrophic factors improve peripheral nerve regeneration.
Biomaterials May, 2019 | Pubmed ID: 30857644
Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect.
Journal of tissue engineering and regenerative medicine Aug, 2019 | Pubmed ID: 31066519
The efficacy and safety of tranexamic acid for reducing blood loss following simultaneous bilateral total knee arthroplasty: a multicenter retrospective study.
BMC musculoskeletal disorders Jul, 2019 | Pubmed ID: 31299945
Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production.
Journal of orthopaedic translation Jul, 2019 | Pubmed ID: 31508317
Modeling appendicular skeletal cartilage development with modified high-density micromass cultures of adult human bone marrow-derived mesenchymal progenitor cells.
Stem cell research & therapy Dec, 2019 | Pubmed ID: 31842986
Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs.
Frontiers in bioengineering and biotechnology , 2019 | Pubmed ID: 31921815
Obesity does not increase blood loss or incidence of immediate postoperative complications during simultaneous total knee arthroplasty: A multicenter study.
The Knee Jun, 2020 | Pubmed ID: 32057638
TGF-β1 plays a protective role in glucocorticoid-induced dystrophic calcification.
Bone Jul, 2020 | Pubmed ID: 32259685
Antimicrobial activity of mesenchymal stem cells against Staphylococcus aureus.
Stem cell research & therapy Jul, 2020 | Pubmed ID: 32680544
Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models.
Biology Jul, 2020 | Pubmed ID: 32751156
Injectable BMP-2 gene-activated scaffold for the repair of cranial bone defect in mice.
Stem cells translational medicine Dec, 2020 | Pubmed ID: 32785966
Mesenchymal stem cell-derived extracellular matrix (mECM): a bioactive and versatile scaffold for musculoskeletal tissue engineering.
Biomedical materials (Bristol, England) Dec, 2020 | Pubmed ID: 32906098
Dead muscle tissue promotes dystrophic calcification by lowering circulating TGF-β1 level.
Bone & joint research Nov, 2020 | Pubmed ID: 33135464
Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling.
Handbook of experimental pharmacology , 2021 | Pubmed ID: 33471201
Development of a large animal rabbit model for chronic periprosthetic joint infection.
Bone & joint research Mar, 2021 | Pubmed ID: 33641351
An in vitro chondro-osteo-vascular triphasic model of the osteochondral complex.
Biomaterials May, 2021 | Pubmed ID: 33798958
A Novel Mouse Model for SNP in Steroid Receptor Co-Activator-1 Reveals Role in Bone Density and Breast Cancer Metastasis.
Endocrinology Aug, 2021 | Pubmed ID: 33963375
Engineering osteoarthritic cartilage model through differentiating senescent human mesenchymal stem cells for testing disease-modifying drugs.
Science China. Life sciences Feb, 2022 | Pubmed ID: 34109475
Urolithin A Protects Chondrocytes From Mechanical Overloading-Induced Injuries.
Frontiers in pharmacology , 2021 | Pubmed ID: 34220525
Graphene oxide-functionalized nanocomposites promote osteogenesis of human mesenchymal stem cells via enhancement of BMP-SMAD1/5 signaling pathway.
Biomaterials Oct, 2021 | Pubmed ID: 34464823
Novel role of estrogen receptor-α on regulating chondrocyte phenotype and response to mechanical loading.
Osteoarthritis and cartilage Feb, 2022 | Pubmed ID: 34767957
Role of Canonical Wnt/β-Catenin Pathway in Regulating Chondrocytic Hypertrophy in Mesenchymal Stem Cell-Based Cartilage Tissue Engineering.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35141220
Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification.
Biomaterials Apr, 2022 | Pubmed ID: 35259584
Human Mesenchymal Stem Cell-Derived Miniature Joint System for Disease Modeling and Drug Testing.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jul, 2022 | Pubmed ID: 35436042
Generation of hyaline-like cartilage tissue from human mesenchymal stromal cells within the self-generated extracellular matrix.
Acta biomaterialia Sep, 2022 | Pubmed ID: 35779770
Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models.
Stem cell research & therapy Aug, 2022 | Pubmed ID: 35927702
Potential Methods of Targeting Cellular Aging Hallmarks to Reverse Osteoarthritic Phenotype of Chondrocytes.
Biology Jun, 2022 | Pubmed ID: 36101377
Experimental models to study osteoarthritis pain and develop therapeutics.
Osteoarthritis and cartilage open Dec, 2022 | Pubmed ID: 36474784
Clinical Applications of Bone Tissue Engineering in Orthopedic Trauma.
Current pathobiology reports Jun, 2018 | Pubmed ID: 36506709
Differences in the intrinsic chondrogenic potential of human mesenchymal stromal cells and iPSC-derived multipotent cells.
Clinical and translational medicine Dec, 2022 | Pubmed ID: 36536500
Pathogenesis of acquired heterotopic ossification: Risk factors, cellular mechanisms, and therapeutic implications.
Bone Dec, 2022 | Pubmed ID: 36581258
Meagan J. Makarcyzk1,2,
Zhong Alan Li1,3,
Ilhan Yu1,
Haruyo Yagi1,
Xiurui Zhang1,
Lauren Yocum1,
Eileen Li1,
Madalyn R. Fritch1,
Qi Gao4,
Bruce A. Bunnell5,
Stuart B. Goodman4,6,
Rocky S. Tuan1,8,
Peter G. Alexander1,7,
Hang Lin1,2,7
1Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine,
2Department of Bioengineering, University of Pittsburgh Swanson School of Engineering,
3Department of Neurobiology, University of Pittsburgh School of Medicine,
4Department of Orthopaedic Surgery, Stanford University,
5Department of Microbiology, Immunology, and Genetics, University of North Texas Health Science Center,
6Department of Bioengineering, Stanford University,
7McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine,
8, The Chinese University of Hong Kong
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