Department of Otolaryngology-Head & Neck Surgery,
Department of Oncology,
The Sidney Kimmel Comprehensive Cancer Center,
Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center
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Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer.
The Journal of clinical endocrinology and metabolism Jan, 2006 | Pubmed ID: 16263813
Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.
The Journal of urology Feb, 2008 | Pubmed ID: 18082200
Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Oct, 2008 | Pubmed ID: 18843024
Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Oct, 2009 | Pubmed ID: 19789364
Association between lifestyle factors and CpG island methylation in a cancer-free population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Nov, 2009 | Pubmed ID: 19861513
KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses.
International journal of cancer Nov, 2010 | Pubmed ID: 20162572
Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Dec, 2010 | Pubmed ID: 21102258
DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation.
Cancer research Feb, 2011 | Pubmed ID: 21266360
Cancer epigenetics: above and beyond.
Toxicology mechanisms and methods May, 2011 | Pubmed ID: 21495866
AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy.
The Prostate Jul, 2012 | Pubmed ID: 22127895
Downregulation of insulin-like growth factor-binding protein 7 in cisplatin-resistant non-small cell lung cancer.
Cancer biology & therapy Feb, 2012 | Pubmed ID: 22277373
Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer.
Epigenetics Jul, 2012 | Pubmed ID: 22694820
Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers.
PloS one , 2012 | Pubmed ID: 23028699
Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.
Cell cycle (Georgetown, Tex.) Apr, 2013 | Pubmed ID: 23435205
Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.
PloS one , 2013 | Pubmed ID: 24086249
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.
Epigenetics Feb, 2014 | Pubmed ID: 24241165
GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer.
The Journal of urology Nov, 2014 | Pubmed ID: 24769028
The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors.
Cancer research Jul, 2014 | Pubmed ID: 24830724
Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine.
Oncotarget May, 2014 | Pubmed ID: 24830820
An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine.
Oncotarget Jul, 2014 | Pubmed ID: 24980822
Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile.
Future oncology (London, England) , 2015 | Pubmed ID: 25066711
Notch1 mutations are drivers of oral tumorigenesis.
Cancer prevention research (Philadelphia, Pa.) Apr, 2015 | Pubmed ID: 25406187
Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.
Cancer prevention research (Philadelphia, Pa.) Mar, 2015 | Pubmed ID: 25586904
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma.
Cancer biology & therapy , 2015 | Pubmed ID: 25756516
Epigenetic silencing of S100A2 in bladder and head and neck cancers.
Oncoscience , 2015 | Pubmed ID: 26097874
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA.
Nature communications Sep, 2015 | Pubmed ID: 26374070
High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing.
Journal of molecular medicine (Berlin, Germany) Sep, 2016 | Pubmed ID: 27030170
Comparative mutational landscape analysis of patient-derived tumour xenografts.
British journal of cancer Feb, 2017 | Pubmed ID: 28118322
Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients.
Oncotarget Feb, 2017 | Pubmed ID: 28147335
Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.
Respiratory medicine Mar, 2017 | Pubmed ID: 28284325
MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients.
Oncotarget Aug, 2017 | Pubmed ID: 28881587
Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma.
Oral oncology Nov, 2017 | Pubmed ID: 28939261
Tobacco and alcohol-induced epigenetic changes in oral carcinoma.
Current opinion in oncology May, 2018 | Pubmed ID: 29538041
Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1.
Cancer letters Oct, 2018 | Pubmed ID: 29964205
Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection.
Clinical chemistry Jan, 2020 | Pubmed ID: 31843869
Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma.
Molecular cancer therapeutics 09, 2020 | Pubmed ID: 32606016
GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma.
Science signaling Aug, 2020 | Pubmed ID: 32817372
Clinical and Prognostic Significance of the Eighth Edition Oral Cancer Staging System.
Cancers Sep, 2022 | Pubmed ID: 36230555
High-risk HPV infection-associated hypermethylated genes in oropharyngeal squamous cell carcinomas.
BMC cancer Nov, 2022 | Pubmed ID: 36344942
Pavan S. Krishnan1,2,
Fernando T. Zamuner1,3,
Carolyn M. Jenks1,
Johnny Y. Xie4,
Lisa Zhang5,
Mohammed Lehar1,
Neal S. Fedarko6,
Mariana Brait1,3,
John P. Carey1
1Department of Otolaryngology-Head & Neck Surgery, Johns Hopkins University School of Medicine,
2, Virginia Commonwealth University School of Medicine,
3Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine,
4Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School,
5Department of Otolaryngology-Head and Neck Surgery, The Ohio State University College of Medicine,
6ICTR Clinical Research Core Laboratory, Johns Hopkins University School of Medicine
SOBRE A JoVE
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