Division of Allergy,
Asthma and Clinical Immunology,
Division of Allergy, Asthma and Clinical Immunology
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Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?
The Journal of allergy and clinical immunology Jun, 2007 | Pubmed ID: 17481717
Eosinophils and asthma.
Current allergy and asthma reports Apr, 2007 | Pubmed ID: 17504657
Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2007 | Pubmed ID: 17548626
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells.
The Journal of experimental medicine Mar, 2008 | Pubmed ID: 18316417
Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung.
Cancer research Oct, 2008 | Pubmed ID: 18922934
Eosinophils in health and disease: the LIAR hypothesis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Apr, 2010 | Pubmed ID: 20447076
Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2011 | Pubmed ID: 22048766
Human versus mouse eosinophils: "That which we call an eosinophil, by any other name would stain as red".
The Journal of allergy and clinical immunology Sep, 2012 | Pubmed ID: 22935586
The expanding role(s) of eosinophils in health and disease.
Blood Nov, 2012 | Pubmed ID: 22936660
Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils.
Journal of leukocyte biology Jul, 2013 | Pubmed ID: 23630390
Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice.
Blood Aug, 2013 | Pubmed ID: 23736699
Predicting response to bacillus Calmette-Guérin (BCG) in patients with carcinoma in situ of the bladder.
Urologic oncology Jan, 2014 | Pubmed ID: 24055426
Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice.
Allergy Mar, 2014 | Pubmed ID: 24266710
Re-defining the unique roles for eosinophils in allergic respiratory inflammation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Sep, 2014 | Pubmed ID: 24961290
Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation.
American journal of respiratory and critical care medicine May, 2017 | Pubmed ID: 27922744
Frontline Science: Eosinophil-deficient MBP-1 and EPX double-knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation.
Journal of leukocyte biology Sep, 2017 | Pubmed ID: 28515227
Sputum autoantibodies in patients with severe eosinophilic asthma.
The Journal of allergy and clinical immunology Apr, 2018 | Pubmed ID: 28751233
Eosinophils promote inducible NOS-mediated lung allograft acceptance.
JCI insight Dec, 2017 | Pubmed ID: 29263310
Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease.
The Journal of allergy and clinical immunology May, 2018 | Pubmed ID: 29374572
Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease.
Journal of leukocyte biology Jul, 2018 | Pubmed ID: 29656559
Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).
Journal of leukocyte biology Jul, 2018 | Pubmed ID: 29672914
Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice.
Communications biology , 2018 | Pubmed ID: 30271964
Baseline Gastrointestinal Eosinophilia Is Common in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy.
Frontiers in immunology , 2018 | Pubmed ID: 30524424
Eosinophil-derived IL-13 promotes emphysema.
The European respiratory journal May, 2019 | Pubmed ID: 30728205
Eosinophil peroxidase, GATA3, and T-bet as tissue biomarkers in chronic rhinosinusitis.
The Journal of allergy and clinical immunology Jun, 2019 | Pubmed ID: 30738839
Intravital imaging allows real-time characterization of tissue resident eosinophils.
Communications biology , 2019 | Pubmed ID: 31098414
Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction.
JCI insight Jun, 2019 | Pubmed ID: 31167966
Deciphering the role of eosinophils in solid organ transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Apr, 2020 | Pubmed ID: 31647606
Intravital imaging of eosinophils: Unwrapping the enigma.
Journal of leukocyte biology 07, 2020 | Pubmed ID: 32170880
Image Analysis of Eosinophil Peroxidase Immunohistochemistry for Diagnosis of Eosinophilic Esophagitis.
Digestive diseases and sciences Mar, 2021 | Pubmed ID: 32248390
M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis.
Science immunology 04, 2020 | Pubmed ID: 32276966
Gastrointestinal Eosinophil Responses in a Longitudinal, Randomized Trial of Peanut Oral Immunotherapy.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jun, 2021 | Pubmed ID: 32434067
Divergent Siglec-F(eights) of mouse and human eosinophil death.
Journal of leukocyte biology Jul, 2020 | Pubmed ID: 32557797
A FACS-based approach to obtain viable eosinophils from human adipose tissue.
Scientific reports 08, 2020 | Pubmed ID: 32764552
Can eosinophils in adipose tissue add fuel to the fire?
Immunology and cell biology Jan, 2021 | Pubmed ID: 33167058
Assessment of Lung Eosinophils In Situ Using Immunohistological Staining.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 33226599
Primary tumors from mucosal barrier organs drive unique eosinophil infiltration patterns and clinical associations.
Oncoimmunology Dec, 2020 | Pubmed ID: 33457078
Eosinophil Shape Change and Secretion.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 33486739
Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production.
Science translational medicine Feb, 2021 | Pubmed ID: 33536281
Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies.
Annual review of immunology Apr, 2021 | Pubmed ID: 33646859
ω-3PUFA supplementation ameliorates adipose tissue inflammation and insulin-stimulated glucose disposal in subjects with obesity: a potential role for apolipoprotein E.
International journal of obesity (2005) Jun, 2021 | Pubmed ID: 33753887
MR1-dependent immune surveillance of the skin contributes to pathogenesis and is a photobiological target of UV light therapy in a mouse model of atopic dermatitis.
Allergy Oct, 2021 | Pubmed ID: 34185885
Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion.
Science (New York, N.Y.) Jul, 2021 | Pubmed ID: 34326208
TLR3-driven IFN-β antagonizes STAT5-activating cytokines and suppresses innate type 2 response in the lung.
The Journal of allergy and clinical immunology Mar, 2022 | Pubmed ID: 34428519
Publisher Correction: A FACS-based approach to obtain viable eosinophils from human adipose tissue.
Scientific reports Sep, 2021 | Pubmed ID: 34561525
Solving the Conundrum of Eosinophils in Alloimmunity.
Transplantation Aug, 2022 | Pubmed ID: 34966103
Hepatic recruitment of eosinophils and their protective function during acute liver injury.
Journal of hepatology Aug, 2022 | Pubmed ID: 35259470
The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4 eosinophils unique to the small intestine.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2022 | Pubmed ID: 35653568
Eosinophils protect against acetaminophen-induced liver injury through cyclooxygenase-mediated IL-4/IL-13 production.
Hepatology (Baltimore, Md.) Feb, 2023 | Pubmed ID: 35714036
Eosinophils promote effector functions of lung group 2 innate lymphoid cells in allergic airway inflammation in mice.
The Journal of allergy and clinical immunology Aug, 2023 | Pubmed ID: 37028525
Eosinophil Peroxidase: A Biomarker for Eosinophilic Chronic Rhinosinusitis Agnostic of Polyp Status.
The Laryngoscope Jan, 2024 | Pubmed ID: 37255054
Safety and Efficacy of Dexpramipexole in Eosinophilic Asthma (EXHALE): A randomized controlled trial.
The Journal of allergy and clinical immunology Nov, 2023 | Pubmed ID: 37277072
Linking adipose tissue eosinophils, interleukin-4, and leptin in human obesity and insulin resistance.
JCI insight Jan, 2024 | Pubmed ID: 38206766
Zhongcheng Mei1,
Mojtaba Taheri1,
Elizabeth A. Jacobsen2,
Wenjun Li3,4,
Andrew E. Gelman3,4,
Daniel Kreisel3,4,
Alexander Sasha Krupnick1,5
1Department of Surgery, University of Maryland Medical Center,
2Division of Allergy, Asthma and Clinical Immunology, Mayo Clinic,
3Department of Surgery, Washington University in St. Louis,
4Department of Pathology & Immunology, Washington University in St. Louis,
5Department of Microbiology and Immunology, University of Maryland Medical Center
SOBRE A JoVE
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