IBE,
Institute of Evolutionary Biology (UPF-CSIC),
Department of Medicine and Life Sciences,
IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences
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Chromosomal speciation and molecular divergence--accelerated evolution in rearranged chromosomes.
Science (New York, N.Y.) Apr, 2003 | Pubmed ID: 12690198
Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation.
Evolution; international journal of organic evolution Mar, 2003 | Pubmed ID: 12703935
Dynamics of a human interparalog gene conversion hotspot.
Genome research May, 2004 | Pubmed ID: 15123583
Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage.
Human genetics Oct, 2004 | Pubmed ID: 15349769
Chromosomal rearrangements and the genomic distribution of gene-expression divergence in humans and chimpanzees.
Trends in genetics : TIG Nov, 2004 | Pubmed ID: 15475109
Geographic stratification of linkage disequilibrium: a worldwide population study in a region of chromosome 22.
Human genomics Nov, 2004 | Pubmed ID: 15606995
Chromosomal rearrangements are associated with higher rates of molecular evolution in mammals.
Gene Jul, 2005 | Pubmed ID: 15951139
Association Cluster Detector: a tool for heuristic detection of significance clusters in whole-genome scans.
Bioinformatics (Oxford, England) Sep, 2005 | Pubmed ID: 16204099
The prion protein gene in humans revisited: lessons from a worldwide resequencing study.
Genome research Feb, 2006 | Pubmed ID: 16369046
The portability of tagSNPs across populations: a worldwide survey.
Genome research Mar, 2006 | Pubmed ID: 16467560
Frequent appearance of novel protein-coding sequences by frameshift translation.
Genomics Dec, 2006 | Pubmed ID: 16890400
Patterns and rates of intron divergence between humans and chimpanzees.
Genome biology , 2007 | Pubmed ID: 17309804
Extreme individual marker F(ST )values do not imply population-specific selection in humans: the NRG1 example.
Human genetics Jul, 2007 | Pubmed ID: 17457614
On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees.
Genome biology , 2007 | Pubmed ID: 17971225
Statistical power analysis of neutrality tests under demographic expansions, contractions and bottlenecks with recombination.
Genetics May, 2008 | Pubmed ID: 18493071
SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data.
Bioinformatics (Oxford, England) Jul, 2008 | Pubmed ID: 18515823
Balancing selection is the main force shaping the evolution of innate immunity genes.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2008 | Pubmed ID: 18606686
The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements.
BMC genomics Aug, 2008 | Pubmed ID: 18699995
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.
PloS one , 2008 | Pubmed ID: 18941528
Allele-specific gene expression is widespread across the genome and biological processes.
PloS one , 2009 | Pubmed ID: 19127300
Interrogating 11 fast-evolving genes for signatures of recent positive selection in worldwide human populations.
Molecular biology and evolution Oct, 2009 | Pubmed ID: 19578157
Genoeconomics: promises and caveats for a new field.
Annals of the New York Academy of Sciences Jun, 2009 | Pubmed ID: 19580553
Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.
BMC genomics Jul, 2009 | Pubmed ID: 19638193
Chromosomal speciation revisited: rearranging theory with pieces of evidence.
Trends in ecology & evolution Nov, 2010 | Pubmed ID: 20817305
Selection upon genome architecture: conservation of functional neighborhoods with changing genes.
PLoS computational biology Oct, 2010 | Pubmed ID: 20949098
Recent human evolution has shaped geographical differences in susceptibility to disease.
BMC genomics Jan, 2011 | Pubmed ID: 21261943
Comparative and demographic analysis of orang-utan genomes.
Nature Jan, 2011 | Pubmed ID: 21270892
Genome-wide association studies pipeline (GWASpi): a desktop application for genome-wide SNP analysis and management.
Bioinformatics (Oxford, England) Jul, 2011 | Pubmed ID: 21586520
Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee.
Genome research Oct, 2011 | Pubmed ID: 21685127
Copy number variation analysis in the great apes reveals species-specific patterns of structural variation.
Genome research Oct, 2011 | Pubmed ID: 21824994
HeT-A_pi1, a piRNA target sequence in the Drosophila telomeric retrotransposon HeT-A, is extremely conserved across copies and species.
PloS one , 2012 | Pubmed ID: 22629389
The genome of melon (Cucumis melo L.).
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22753475
Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis.
Journal of medical genetics Jan, 2013 | Pubmed ID: 23160276
Accelerated exon evolution within primate segmental duplications.
Genome biology Jan, 2013 | Pubmed ID: 23360670
The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild.
BMC genomics May, 2013 | Pubmed ID: 23721540
High trans-ethnic replicability of GWAS results implies common causal variants.
PLoS genetics Jun, 2013 | Pubmed ID: 23785302
Great ape genetic diversity and population history.
Nature Jul, 2013 | Pubmed ID: 23823723
Application of multi-SNP approaches Bayesian LASSO and AUC-RF to detect main effects of inflammatory-gene variants associated with bladder cancer risk.
PloS one , 2013 | Pubmed ID: 24391818
Pool and conquer: new tricks for (c)old problems.
Molecular ecology Apr, 2014 | Pubmed ID: 24667009
Genome-wide analysis of wild-type Epstein-Barr virus genomes derived from healthy individuals of the 1,000 Genomes Project.
Genome biology and evolution Apr, 2014 | Pubmed ID: 24682154
Genomic analysis of the blood attributed to Louis XVI (1754-1793), king of France.
Scientific reports Apr, 2014 | Pubmed ID: 24763138
Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.
PloS one , 2014 | Pubmed ID: 24818791
Interplay of interlocus gene conversion and crossover in segmental duplications under a neutral scenario.
G3 (Bethesda, Md.) Jun, 2014 | Pubmed ID: 24906640
Mendelian genes for Parkinson's disease contribute to the sporadic forms of the disease.
Human molecular genetics Apr, 2015 | Pubmed ID: 25504046
Analysis of Five Gene Sets in Chimpanzees Suggests Decoupling between the Action of Selection on Protein-Coding and on Noncoding Elements.
Genome biology and evolution May, 2015 | Pubmed ID: 25977458
Genetic and Clinical Factors Associated with Chronic Postsurgical Pain after Hernia Repair, Hysterectomy, and Thoracotomy: A Two-year Multicenter Cohort Study.
Anesthesiology May, 2015 | Pubmed ID: 25985024
The European Genome-phenome Archive of human data consented for biomedical research.
Nature genetics Jul, 2015 | Pubmed ID: 26111507
SeDuS: segmental duplication simulator.
Bioinformatics (Oxford, England) Jan, 2016 | Pubmed ID: 26358728
Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.
Neurology(R) neuroimmunology & neuroinflammation Oct, 2015 | Pubmed ID: 26445728
267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation.
Molecular biology and evolution May, 2016 | Pubmed ID: 26764160
Functional Implications of Human-Specific Changes in Great Ape microRNAs.
PloS one , 2016 | Pubmed ID: 27105073
Assessing statistical significance in multivariable genome wide association analysis.
Bioinformatics (Oxford, England) Jul, 2016 | Pubmed ID: 27153677
Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions.
Genome biology and evolution Jul, 2016 | Pubmed ID: 27345955
Differences in molecular evolutionary rates among microRNAs in the human and chimpanzee genomes.
BMC genomics Jul, 2016 | Pubmed ID: 27474039
Chimpanzee genomic diversity reveals ancient admixture with bonobos.
Science (New York, N.Y.) Oct, 2016 | Pubmed ID: 27789843
Natural Selection in the Great Apes.
Molecular biology and evolution Dec, 2016 | Pubmed ID: 27795229
Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies.
Scientific reports Nov, 2016 | Pubmed ID: 27892471
Properties of human disease genes and the role of genes linked to Mendelian disorders in complex disease aetiology.
Human molecular genetics Feb, 2017 | Pubmed ID: 28053046
Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.
Brain structure & function Sep, 2017 | Pubmed ID: 28317062
Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies.
Brain pathology (Zurich, Switzerland) May, 2018 | Pubmed ID: 28321951
Erratum to: Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.
Brain structure & function Sep, 2017 | Pubmed ID: 28488187
Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples.
PloS one , 2017 | Pubmed ID: 28654678
Antagonistic pleiotropy and mutation accumulation influence human senescence and disease.
Nature ecology & evolution Jan, 2017 | Pubmed ID: 28812720
The impact of endogenous content, replicates and pooling on genome capture from faecal samples.
Molecular ecology resources Mar, 2018 | Pubmed ID: 29058768
A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0).
GigaScience Nov, 2017 | Pubmed ID: 29092041
NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) Oct, 2018 | Pubmed ID: 29117789
Potential damaging mutation in LRP5 from genome sequencing of the first reported chimpanzee with the Chiari malformation.
Scientific reports Nov, 2017 | Pubmed ID: 29123202
Similar genomic proportions of copy number variation within gray wolves and modern dog breeds inferred from whole genome sequencing.
BMC genomics Dec, 2017 | Pubmed ID: 29258433
Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.
Scientific reports Feb, 2018 | Pubmed ID: 29472617
Author Correction: Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.
Scientific reports Apr, 2018 | Pubmed ID: 29662094
Replicability and Prediction: Lessons and Challenges from GWAS.
Trends in genetics : TIG Jul, 2018 | Pubmed ID: 29716745
Author Correction: Potential damaging mutation in LRP5 from genome sequencing of the first reported chimpanzee with the Chiari malformation.
Scientific reports May, 2018 | Pubmed ID: 29728620
Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis.
Molecular biology and evolution Aug, 2018 | Pubmed ID: 29788292
Effect of Collapsed Duplications on Diversity Estimates: What to Expect.
Genome biology and evolution Nov, 2018 | Pubmed ID: 30364947
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Nature genetics Feb, 2019 | Pubmed ID: 30643258
A pharmacogenetic study implicates in the response to Interferon-β in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) Aug, 2020 | Pubmed ID: 31221001
Reply to: Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease.
Nature ecology & evolution Jul, 2019 | Pubmed ID: 31235924
Genome-phenome explorer (GePhEx): a tool for the visualization and interpretation of phenotypic relationships supported by genetic evidence.
Bioinformatics (Oxford, England) Feb, 2020 | Pubmed ID: 31393550
Leveraging European infrastructures to access 1 million human genomes by 2022.
Nature reviews. Genetics Nov, 2019 | Pubmed ID: 31455890
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.
Nature reviews. Genetics Nov, 2019 | Pubmed ID: 31520075
Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet.
Current biology : CB Jan, 2020 | Pubmed ID: 31839456
A New Risk Variant for Multiple Sclerosis at 11q23.3 Is Associated with Expansion of Circulating Regulatory T Cells.
Journal of clinical medicine Feb, 2020 | Pubmed ID: 32110891
Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta).
PLoS genetics May, 2020 | Pubmed ID: 32392208
Extreme differences between human germline and tumor mutation densities are driven by ancestral human-specific deviations.
Nature communications May, 2020 | Pubmed ID: 32427823
The shared genetic architecture of schizophrenia, bipolar disorder and lifespan.
Human genetics Mar, 2021 | Pubmed ID: 32772156
Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches.
Microorganisms Oct, 2020 | Pubmed ID: 33138327
The Presence of Human Herpesvirus 6 in the Brain in Health and Disease.
Biomolecules Nov, 2020 | Pubmed ID: 33172107
Variation in predicted COVID-19 risk among lemurs and lorises.
bioRxiv : the preprint server for biology Feb, 2021 | Pubmed ID: 33564767
Variation in predicted COVID-19 risk among lemurs and lorises.
American journal of primatology Jun, 2021 | Pubmed ID: 33792947
Inversions and genomic differentiation after secondary contact: When drift contributes to maintenance, not loss, of differentiation.
Evolution; international journal of organic evolution Jun, 2021 | Pubmed ID: 33844299
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures.
Nature communications May, 2021 | Pubmed ID: 34035253
Genetic Predisposition to Alzheimer's Disease Is Associated with Enlargement of Perivascular Spaces in Centrum Semiovale Region.
Genes May, 2021 | Pubmed ID: 34072165
Comparative Analysis of Mammal Genomes Unveils Key Genomic Variability for Human Life Span.
Molecular biology and evolution Oct, 2021 | Pubmed ID: 34297086
Coexpression of the discoidin domain receptor 1 gene with oligodendrocyte-related and schizophrenia risk genes in the developing and adult human brain.
Brain and behavior Aug, 2021 | Pubmed ID: 34323026
The genetic impact of an Ebola outbreak on a wild gorilla population.
BMC genomics Oct, 2021 | Pubmed ID: 34635054
Single-cell Transcriptional Changes in Neurodegenerative Diseases.
Neuroscience Dec, 2021 | Pubmed ID: 34748859
Correction: Telford et al. Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches. 2020, , 1686.
Microorganisms Nov, 2021 | Pubmed ID: 34835535
GA4GH: International policies and standards for data sharing across genomic research and healthcare.
Cell genomics Nov, 2021 | Pubmed ID: 35072136
International federation of genomic medicine databases using GA4GH standards.
Cell genomics Nov, 2021 | Pubmed ID: 35128509
Beacon v2 and Beacon networks: A "lingua franca" for federated data discovery in biomedical genomics, and beyond.
Human mutation Jun, 2022 | Pubmed ID: 35297548
Human herpesvirus diversity is altered in HLA class I binding peptides.
Proceedings of the National Academy of Sciences of the United States of America May, 2022 | Pubmed ID: 35486690
Prepandemic Alzheimer Disease Biomarkers and Anxious-Depressive Symptoms During the COVID-19 Confinement in Cognitively Unimpaired Adults.
Neurology Oct, 2022 | Pubmed ID: 35918160
Author Correction: Comparative and demographic analysis of orang-utan genomes.
Nature Aug, 2022 | Pubmed ID: 35962045
Look-alike humans identified by facial recognition algorithms show genetic similarities.
Cell reports Aug, 2022 | Pubmed ID: 36001980
Genetically predicted telomere length and its relationship with neurodegenerative diseases and life expectancy.
Computational and structural biotechnology journal , 2022 | Pubmed ID: 36051868
Brain transcriptomic profiling reveals common alterations across neurodegenerative and psychiatric disorders.
Computational and structural biotechnology journal , 2022 | Pubmed ID: 36090817
Genetically predicted telomere length and Alzheimer's disease endophenotypes: a Mendelian randomization study.
Alzheimer's research & therapy Nov, 2022 | Pubmed ID: 36345036
Polygenic risk scores enhance prediction of body mass index increase in individuals with a first episode of psychosis.
European psychiatry : the journal of the Association of European Psychiatrists Feb, 2023 | Pubmed ID: 36852609
Evolutionary constraint and innovation across hundreds of placental mammals.
Science (New York, N.Y.) Apr, 2023 | Pubmed ID: 37104599
The landscape of tolerated genetic variation in humans and primates.
bioRxiv : the preprint server for biology May, 2023 | Pubmed ID: 37205491
The landscape of tolerated genetic variation in humans and primates.
Science (New York, N.Y.) Jun, 2023 | Pubmed ID: 37262156
A global catalog of whole-genome diversity from 233 primate species.
Science (New York, N.Y.) Jun, 2023 | Pubmed ID: 37262161
Understanding the neurological implications of acute and long COVID using brain organoids.
Disease models & mechanisms Jul, 2023 | Pubmed ID: 37458167
CAAStools: a toolbox to identify and test Convergent Amino Acid Substitutions.
Bioinformatics (Oxford, England) Oct, 2023 | Pubmed ID: 37846039
Identification of constrained sequence elements across 239 primate genomes.
Nature Jan, 2024 | Pubmed ID: 38030727
Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum.
Alzheimer's & dementia : the journal of the Alzheimer's Association Dec, 2023 | Pubmed ID: 38088508
Luciano Fiore1,2,
Jan Arderiu3,
Andrea Martí-Sarrias3,4,
Isabel Turpín3,4,
Ruth I. Pareja3,5,
Arcadi Navarro5,6,7,8,
Mariana Holubiec2,9,
Julieta Bianchelli9,
Tomas Falzone2,9,
Gonzalo Spelzini1,2,
Gabriel Scicolone1,2,
Sandra Acosta3,4
1Instituto de Biología Celular y Neurociencias “Prof. E. De Robertis” (IBCN), CONICET - Universidad de Buenos Aires,
2Facultad de Medicina, Departamento de Biología Celular, Histología, Embriología y Genética, Universidad de Buenos Aires,
3Institute of Neurosciences, Pathology and Experimental Therapeutics Dept, University of Barcelona,
4Functional Neurogenomics Group, Neurodevelopmental Disorders, IDIBELL, L’Hospitalet de Llobregat,
5IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra,
6, Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra,
7Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology,
8BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation,
9, Instituto de Investigación en Biomedicina (IBioBA) – CONICET – Instituto Partner de la Sociedad Max Planck
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