Translational Research Institute
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Targeting White Adipose Tissue with Exercise or Bariatric Surgery as Therapeutic Strategies in Obesity.
Biology Mar, 2019 | Pubmed ID: 30875990
Endurance training remodels skeletal muscle phospholipid composition and increases intrinsic mitochondrial respiration in men with Type 2 diabetes.
Physiological genomics Nov, 2019 | Pubmed ID: 31588872
Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality.
Nutrients Oct, 2019 | Pubmed ID: 31652734
Plasma Myokine Concentrations After Acute Exercise in Non-obese and Obese Sedentary Women.
Frontiers in physiology , 2020 | Pubmed ID: 32132925
An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression.
Physiological reports Jun, 2020 | Pubmed ID: 32562350
Individual Response Variation in the Effects of Weight Loss and Exercise on Insulin Sensitivity and Cardiometabolic Risk in Older Adults.
Frontiers in endocrinology , 2020 | Pubmed ID: 33013705
A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function.
Circulation Jan, 2021 | Pubmed ID: 33106031
Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial.
Obesity (Silver Spring, Md.) Jun, 2021 | Pubmed ID: 34029448
A Metabolomic Signature of Glucagon Action in Healthy Individuals With Overweight/Obesity.
Journal of the Endocrine Society Sep, 2021 | Pubmed ID: 34337278
Twenty-four hour assessments of substrate oxidation reveal differences in metabolic flexibility in type 2 diabetes that are improved with aerobic training.
Diabetologia Oct, 2021 | Pubmed ID: 34402932
The Metabolic Significance of Intermuscular Adipose Tissue: Is IMAT a Friend or a Foe to Metabolic Health?
Diabetes Nov, 2021 | Pubmed ID: 34711670
Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults.
American journal of physiology. Endocrinology and metabolism Mar, 2022 | Pubmed ID: 35068187
Aerobic training increases mitochondrial respiratory capacity in human skeletal muscle stem cells from sedentary individuals.
American journal of physiology. Cell physiology Aug, 2022 | Pubmed ID: 35785986
Single cell full-length transcriptome of human subcutaneous adipose tissue reveals unique and heterogeneous cell populations.
iScience Aug, 2022 | Pubmed ID: 35992069
Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary.
GeroScience Feb, 2023 | Pubmed ID: 36242693
Mitochondrial Energetics in Skeletal Muscle Are Associated With Leg Power and Cardiorespiratory Fitness in the Study of Muscle, Mobility and Aging.
The journals of gerontology. Series A, Biological sciences and medical sciences Aug, 2023 | Pubmed ID: 36462195
Intermuscular adipose tissue in metabolic disease.
Nature reviews. Endocrinology May, 2023 | Pubmed ID: 36564490
The mitochondrial multi-omic response to exercise training across tissues.
bioRxiv : the preprint server for biology Jan, 2023 | Pubmed ID: 36711881
Isolation of nuclei from frozen human subcutaneous adipose tissue for full-length single-nuclei transcriptional profiling.
STAR protocols Mar, 2023 | Pubmed ID: 36853719
Schwann cells contribute to demyelinating diabetic neuropathy and nerve terminal structures in white adipose tissue.
iScience Mar, 2023 | Pubmed ID: 36895649
Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues.
bioRxiv : the preprint server for biology Oct, 2023 | Pubmed ID: 37214953
Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity.
American journal of physiology. Endocrinology and metabolism Oct, 2023 | Pubmed ID: 37584609
Editorial: Exercise intervention for prevention and management of type 2 diabetes.
Frontiers in physiology , 2023 | Pubmed ID: 37936578
Translating In Vitro Models of Exercise in Human Muscle Cells: A Mitocentric View.
Exercise and sport sciences reviews Jan, 2024 | Pubmed ID: 38126401
Effects of resveratrol on circadian clock gene expression in young and older human adipose-derived progenitor cells.
Aging Jan, 2024 | Pubmed ID: 38189848
Understanding the variation in exercise responses to guide personalized physical activity prescriptions.
Cell metabolism Apr, 2024 | Pubmed ID: 38262420
Percutaneous biopsies of skeletal muscle and adipose tissue in individuals older than 70: methods and outcomes in the Study of Muscle, Mobility and Aging (SOMMA).
GeroScience Jun, 2024 | Pubmed ID: 38315316
Distinct subpopulations of human subcutaneous adipose tissue precursor cells revealed by single-cell RNA sequencing.
American journal of physiology. Cell physiology Apr, 2024 | Pubmed ID: 38581663
Muscle mitochondrial bioenergetic capacities are associated with multimorbidity burden in older adults: the Study of Muscle, Mobility and Aging (SOMMA).
The journals of gerontology. Series A, Biological sciences and medical sciences Apr, 2024 | Pubmed ID: 38605684
Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue.
Nature metabolism May, 2024 | Pubmed ID: 38693320
Line O. Elingaard-Larsen1,2,
Katie L. Whytock1,
Adeline Divoux1,
Meghan Hopf1,
Erin E. Kershaw3,
Jamie N. Justice4,
Bret H. Goodpaster1,
Nancy E. Lane5,
Lauren M. Sparks1
1Translational Research Institute, AdventHealth,
2, Steno Diabetes Center Copenhagen,
3Division of Endocrinology and Metabolism, University of Pittsburgh,
4Gerontology and Geriatric Medicine, Wake Forest University School of Medicine,
5Department of Internal Medicine - Rheumatology, Allergy, and Clinical Immunology, University of California Davis Health
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