Barbara Baird

Bivalent ligands with rigid double-stranded DNA spacers reveal structural constraints on signaling by Fc epsilon RI.

Antigen-stimulated trafficking from the recycling compartment to the plasma membrane in RBL mast cells.

A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation.

Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcepsilonRI.

Ordered and disordered phases coexist in plasma membrane vesicles of RBL-2H3 mast cells. An ESR study.

Highly effective poly(ethylene glycol) architectures for specific inhibition of immune receptor activation.

Visualization of plasma membrane compartmentalization with patterned lipid bilayers.

In situ measurement of degranulation as a biosensor based on RBL-2H3 mast cells.

Reconstitution of regulated phosphorylation of FcepsilonRI by a lipid raft-excluded protein-tyrosine phosphatase.

Oligo(ethylene glycol) containing polymer brushes as bioselective surfaces.

Bright and stable core-shell fluorescent silica nanoparticles.

High spatial resolution observation of single-molecule dynamics in living cell membranes.

Lipid segregation and IgE receptor signaling: a decade of progress.

Transmembrane sequences are determinants of immunoreceptor signaling.

Antigen-decorated shell cross-linked nanoparticles: synthesis, characterization, and antibody interactions.

Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells.

Dinitrophenyl ligand substrates and their application to immunosensors.

Coexisting domains in the plasma membranes of live cells characterized by spin-label ESR spectroscopy.

Functionalized surface arrays for spatial targeting of immune cell signaling.

Core/Shell fluorescent silica nanoparticles for chemical sensing: towards single-particle laboratories.

Fluorescence resonance energy transfer between lipid probes detects nanoscopic heterogeneity in the plasma membrane of live cells.

Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles.

Insights into immunoglobulin E receptor signaling from structurally defined ligands.

Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays.

Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function.

Patterned biofunctional poly(acrylic acid) brushes on silicon surfaces.

Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles.

Trivalent ligands with rigid DNA spacers reveal structural requirements for IgE receptor signaling in RBL mast cells.

Binding mechanisms of PEGylated ligands reveal multiple effects of the PEG scaffold.

Real-time cross-correlation image analysis of early events in IgE receptor signaling.

Critical fluctuations in plasma membrane vesicles.

Nanobiotechnology and cell biology: micro- and nanofabricated surfaces to investigate receptor-mediated signaling.

Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.

Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays.

Roles for SH2 and SH3 domains in Lyn kinase association with activated FcepsilonRI in RBL mast cells revealed by patterned surface analysis.

IgE receptor-mediated alteration of membrane-cytoskeleton interactions revealed by mass spectrometric analysis of detergent-resistant membranes.

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.

Preventing nonspecific adsorption on polymer brush covered gold electrodes using a modified ATRP initiator.

Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins.

Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells.

A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.

Highly Aminated Mesoporous Silica Nanoparticles with Cubic Pore Structure.

Sphingosine derivatives inhibit cell signaling by electrostatically neutralizing polyphosphoinositides at the plasma membrane.

An array of planar apertures for near-field fluorescence correlation spectroscopy.

Cellular responses to patterned poly(acrylic acid) brushes.

Micropatterned ligand arrays to study spatial regulation in Fc receptor signaling.

Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)Pâ‚‚ between distinct membrane pools.

2D-ELDOR study of heterogeneity and domain structure changes in plasma membrane vesicles upon cross-linking of receptors.

Sequestration of phosphoinositides by mutated MARCKS effector domain inhibits stimulated Ca(2+) mobilization and degranulation in mast cells.

Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting.

Spatiotemporal resolution of mast cell granule exocytosis reveals correlation with Ca2+ wave initiation.

Quantitative nanoscale analysis of IgE-FcεRI clustering and coupling to early signaling proteins.

Roles for ca(2+) mobilization and its regulation in mast cell functions.

Molecular mechanisms of spontaneous and directed mast cell motility.