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Pathogenomique Mycobacterienne Integrée
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Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis.
The FEBS journal Apr, 2007 | Pubmed ID: 17371506
Identification of the missing trans-acting enoyl reductase required for phthiocerol dimycocerosate and phenolglycolipid biosynthesis in Mycobacterium tuberculosis.
Journal of bacteriology Jul, 2007 | Pubmed ID: 17468241
ESX/type VII secretion systems and their role in host-pathogen interaction.
Current opinion in microbiology Feb, 2009 | Pubmed ID: 19155186
Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants.
BioEssays : news and reviews in molecular, cellular and developmental biology Apr, 2009 | Pubmed ID: 19274661
Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis.
The FEBS journal Jun, 2010 | Pubmed ID: 20553505
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.
The Journal of infectious diseases Apr, 2011 | Pubmed ID: 21196469
Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity.
Infection and immunity Jul, 2011 | Pubmed ID: 21576344
p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21646350
Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.
PLoS pathogens Feb, 2012 | Pubmed ID: 22319448
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.
Molecular microbiology Mar, 2012 | Pubmed ID: 22340629
Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies.
Emerging infectious diseases Apr, 2012 | Pubmed ID: 22469053
Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential.
Cell host & microbe Apr, 2012 | Pubmed ID: 22520463
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
Autophagy Sep, 2012 | Pubmed ID: 22885411
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis.
Nature genetics Feb, 2013 | Pubmed ID: 23291586
Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.
PloS one , 2013 | Pubmed ID: 23536839
Institut Pasteur, Paris, France
Charlotte Keller*,1,
Nora Mellouk*,1,
Anne Danckaert2,
Roxane Simeone3,
Roland Brosch3,
Jost Enninga1,
Alexandre Bobard1
1Dynamique des Interactions Hôte Pathogène, Institut Pasteur, Paris, France,
2Imagopole, Institut Pasteur, Paris, France,
3Pathogenomique Mycobacterienne Integrée, Institut Pasteur, Paris, France
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