Tatsuro Kohno

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn.

A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain.

Central sensitization and LTP: do pain and memory share similar mechanisms?

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn.

Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.

Action of isoflurane on the substantia gelatinosa neurons of the adult rat spinal cord.

The NR3B subunit does not alter the anesthetic sensitivities of recombinant N-methyl-D-aspartate receptors.

Effect of agmatine on heteromeric N-methyl-D-aspartate receptor channels.

Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord.

Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.

Different effects of opioid and cannabinoid receptor agonists on C-fiber-induced extracellular signal-regulated kinase activation in dorsal horn neurons in normal and spinal nerve-ligated rats.

Actions of norepinephrine and isoflurane on inhibitory synaptic transmission in adult rat spinal cord substantia gelatinosa neurons.

Effects of ketamine on acute somatic nociception in wild-type and N-methyl-D-aspartate (NMDA) receptor epsilon1 subunit knockout mice.

Actions of midazolam on excitatory transmission in dorsal horn neurons of adult rat spinal cord.

Recent advances in basic neurosciences and brain disease: from synapses to behavior.

Nitrous oxide inhibits glutamatergic transmission in spinal dorsal horn neurons.

Mutation of alpha1G T-type calcium channels in mice does not change anesthetic requirements for loss of the righting reflex and minimum alveolar concentration but delays the onset of anesthetic induction.

Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model.

[Function of spinal GABA receptor and its modulation].

[Opioids and spinal analgesia].

Differential presynaptic effects of opioid agonists on Adelta- and C-afferent glutamatergic transmission to the spinal dorsal horn.

Taurine activates glycine and gamma-aminobutyric acid A receptors in rat substantia gelatinosa neurons.

Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity.

Action of dexmedetomidine on the substantia gelatinosa neurons of the rat spinal cord.

[Sudden vocal cord closure during general anesthesia using remifentanil].

Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia.

Nitrous oxide and the inhibitory synaptic transmission in rat dorsal horn neurons.

Reduced immobilizing properties of isoflurane and nitrous oxide in mutant mice lacking the N-methyl-D-aspartate receptor GluR(epsilon)1 subunit are caused by the secondary effects of gene knockout.

Bupivacaine inhibits glutamatergic transmission in spinal dorsal horn neurons.

Neuropathic pain and neuron-glia interactions in the spinal cord.

Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons.

[Case of hyperkalemia after the administration of hypertonic mannitol during craniotomy].

[Case of profound bradycardia and cardiac arrest during left upper lobectomy and lymph node dissection].

[Case of airway management by laryngeal mask airway for a child with laryngeal web undergoing adenotonsillectomy].

Electrophysiological analysis of vulnerability to experimental ischemia in neonatal rat spinal ventral horn neurons.

Zaltoprofen inhibits bradykinin-mediated enhancement of glutamate receptor activity in substantia gelatinosa neurons.

[Anesthetic mechanisms in the spinal cord].

Reduction of spinal cord ischemia/reperfusion injury with simvastatin in rats.

Acute airway obstruction and tracheal laceration during gastrostomy placement in an infant with tracheoesophageal fistula.

Effect of xenon on excitatory and inhibitory transmission in rat spinal ventral horn neurons.

[Mechanisms of action of therapeutic agents in the treatment of chronic pain in the spinal cord].

[Local anesthetics inhibit NMDA-mediated glutamatergic transmission in spinal dorsal horn neurons].

The mu opioid receptor modulates neurotransmission in the rat spinal ventral horn.

Milnacipran inhibits glutamatergic N-methyl-D-aspartate receptor activity in spinal dorsal horn neurons.

When similar is not alike: decreased sensory thresholds after intravenous infusion of remifentanil may not be remifentanil-induced hyperalgesia.

Increased brain monoaminergic tone after the NMDA receptor GluN2A subunit gene knockout is responsible for resistance to the hypnotic effect of nitrous oxide.

A case of respiratory distress syndrome in a newborn immediately after induction of anesthesia.

[Antagonistic action of local anesthetics except at the sodium channel].