Division of Reproductive Sciences,
Division of Developmental Biology,
Perinatal Institute,
Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute
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Expression of flap endonuclease-1 during meiosis in a basidiomycete, Coprinus cinereus.
Fungal genetics and biology : FG & B May, 2004 | Pubmed ID: 15050538
[Latest frontiers of meiosis research in Coprinus cinereus].
Seikagaku. The Journal of Japanese Biochemical Society Nov, 2004 | Pubmed ID: 15626033
DNA topoisomerase II interacts with Lim15/Dmc1 in meiosis.
Nucleic acids research , 2005 | Pubmed ID: 16221977
Knockdown of LIM15/DMC1 in the mushroom Coprinus cinereus by double-stranded RNA-mediated gene silencing.
Microbiology (Reading, England) Nov, 2005 | Pubmed ID: 16272388
Postmeiotic sex chromatin in the male germline of mice.
Current biology : CB Apr, 2006 | Pubmed ID: 16581510
Sumoylation of a meiosis-specific RecA homolog, Lim15/Dmc1, via interaction with the small ubiquitin-related modifier (SUMO)-conjugating enzyme Ubc9.
The FEBS journal Sep, 2006 | Pubmed ID: 16879611
Proliferating cell nuclear antigen (PCNA) interacts with a meiosis-specific RecA homologues, Lim15/Dmc1, but does not stimulate its strand transfer activity.
Biochemical and biophysical research communications Jan, 2007 | Pubmed ID: 17157821
A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis.
PLoS genetics Apr, 2007 | Pubmed ID: 17447844
Sex chromosome silencing in the marsupial male germ line.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2007 | Pubmed ID: 17535928
Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1: a molecular link between recombination and chromatin assembly during meiosis.
The FEBS journal May, 2008 | Pubmed ID: 18355319
Coprinus cinereus Mer3 is required for synaptonemal complex formation during meiosis.
Chromosoma Feb, 2009 | Pubmed ID: 18841377
Telomeric RNAs mark sex chromosomes in stem cells.
Genetics Jul, 2009 | Pubmed ID: 19380904
XY and ZW: is meiotic sex chromosome inactivation the rule in evolution?
PLoS genetics May, 2009 | Pubmed ID: 19461890
Two-step imprinted X inactivation: repeat versus genic silencing in the mouse.
Molecular and cellular biology Jul, 2010 | Pubmed ID: 20404085
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.
PloS one , 2010 | Pubmed ID: 21072209
Detection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos.
Nature protocols Mar, 2011 | Pubmed ID: 21372809
MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells.
Genes & development May, 2011 | Pubmed ID: 21536735
X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells.
Human genetics Aug, 2011 | Pubmed ID: 21667284
Human postmeiotic sex chromatin and its impact on sex chromosome evolution.
Genome research May, 2012 | Pubmed ID: 22375025
Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways.
Cellular and molecular life sciences : CMLS Aug, 2012 | Pubmed ID: 22382926
The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.
The Journal of biological chemistry Jul, 2012 | Pubmed ID: 22665486
RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.
Genes & development Dec, 2012 | Pubmed ID: 23249736
The great escape: Active genes on inactive sex chromosomes and their evolutionary implications.
Epigenetics : official journal of the DNA Methylation Society Sep, 2013 | Pubmed ID: 23880818
MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells.
Stem cells (Dayton, Ohio) Nov, 2013 | Pubmed ID: 23897718
BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.
The Journal of cell biology Jun, 2014 | Pubmed ID: 24914237
SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.
Developmental cell Mar, 2015 | Pubmed ID: 25703348
Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.
Stem cells (Dayton, Ohio) Jul, 2015 | Pubmed ID: 25917546
Functional significance of the sex chromosomes during spermatogenesis.
Reproduction (Cambridge, England) Jun, 2015 | Pubmed ID: 25948089
BAZ1B is dispensable for H2AX phosphorylation on Tyrosine 142 during spermatogenesis.
Biology open May, 2015 | Pubmed ID: 25979708
FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.
Human molecular genetics Sep, 2015 | Pubmed ID: 26123487
Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline.
BMC biology Jul, 2015 | Pubmed ID: 26198001
Fancb deficiency impairs hematopoietic stem cell function.
Scientific reports Dec, 2015 | Pubmed ID: 26658157
Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.
Cell reports 10, 2016 | Pubmed ID: 27760317
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Scientific reports 04, 2017 | Pubmed ID: 28378742
Polycomb directs timely activation of germline genes in spermatogenesis.
Genes & development 08, 2017 | Pubmed ID: 28924034
Dynamic reorganization of open chromatin underlies diverse transcriptomes during spermatogenesis.
Nucleic acids research 01, 2018 | Pubmed ID: 29126117
CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice.
Human molecular genetics 04, 2018 | Pubmed ID: 29360988
RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes.
PLoS genetics 02, 2018 | Pubmed ID: 29462142
Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline.
Proceedings of the National Academy of Sciences of the United States of America 05, 2018 | Pubmed ID: 29686098
Epigenomic and single-cell profiling of human spermatogonial stem cells.
Stem cell investigation , 2018 | Pubmed ID: 29782571
SCML2 promotes heterochromatin organization in late spermatogenesis.
Journal of cell science 09, 2018 | Pubmed ID: 30097555
A rapidly evolved domain, the SCML2 DNA-binding repeats, contributes to chromatin binding of mouse SCML2†.
Biology of reproduction 02, 2019 | Pubmed ID: 30137219
Chromosome Spread Analyses of Meiotic Sex Chromosome Inactivation.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 30218364
XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†.
Biology of reproduction 03, 2019 | Pubmed ID: 30289439
Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development.
Nature structural & molecular biology 03, 2019 | Pubmed ID: 30778237
UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells.
Nature communications 10, 2019 | Pubmed ID: 31624244
The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis.
Current biology : CB 02, 2020 | Pubmed ID: 31902729
BRUCE preserves genomic stability in the male germline of mice.
Cell death and differentiation Aug, 2020 | Pubmed ID: 32139899
FANCD2 is required for the repression of germline transposable elements.
Reproduction (Cambridge, England) 06, 2020 | Pubmed ID: 32163912
Licensing meiotic progression†.
Biology of reproduction 06, 2020 | Pubmed ID: 32338765
Endogenous retroviruses drive species-specific germline transcriptomes in mammals.
Nature structural & molecular biology 10, 2020 | Pubmed ID: 32895553
Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition.
Nature structural & molecular biology 10, 2020 | Pubmed ID: 32895557
Yu-Han Yeh*,1,2,
Mengwen Hu*,1,2,
Toshinori Nakagawa3,4,
Akihiko Sakashita1,2,
Shosei Yoshida3,4,
So Maezawa5,6,
Satoshi H. Namekawa1,2
1Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center,
2Department of Pediatrics, University of Cincinnati College of Medicine,
3Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences,
4Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai),
5Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University,
6Faculty of Science and Technology, Department of Applied Biological Science, Tokyo University of Science
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