Erik Serrao

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors.

HIV-1 integrase inhibitors: 2007-2008 update.

A Symmetric Region of the HIV-1 Integrase Dimerization Interface Is Essential for Viral Replication.

Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.

Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.

Biochemical characterization of novel retroviral integrase proteins.

Alteration of select gene expression patterns in individuals infected with HIV-1.

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding.

Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75.

Molecular mechanisms of retroviral integration site selection.

Host and viral determinants for MxB restriction of HIV-1 infection.

Key determinants of target DNA recognition by retroviral intasomes.

Structural basis for retroviral integration into nucleosomes.

Sites of retroviral DNA integration: From basic research to clinical applications.

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.