Leandro Castellano

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.

Bendamustine as a model for the activity of alkylating agents.

CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions.

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response.

No evidence for a viral association or aetiology in pancreatic cancer.

No evidence for a polyomavirus association or aetiology in AIDS-associated nonsmall cell lung cancer.

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.

Determination of cut-offs for circulating tumor cell measurement in metastatic cancer.

microRNAs as markers of survival and chemoresistance in pancreatic ductal adenocarcinoma.

Integrated analysis of miRNA and mRNA profiles enables target acquisition in human cancers.

MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors.

The clinico-pathologic role of microRNAs miR-9 and miR-151-5p in breast cancer metastasis.

miRNAs in breast cancer: ready for real time?

Transcriptome-level microarray expression profiling implicates IGF-1 and Wnt signalling dysregulation in the pathogenesis of thyroid-associated orbitopathy.

Retinoblastoma protein determines aggressiveness in triple-negative breast cancer.

The role of miR-10b in metastatic pancreatic ductal adenocarcinoma.

Loss of miR-126 is crucial to pancreatic cancer progression.

Breast cancer treatment and adverse cardiac events: what are the molecular mechanisms?.

Defining a prognostic molecular profile for ductal adenocarcinoma of the pancreas highlights known key signaling pathways.

Towards a clinical use of miRNAs in pancreatic cancer biopsies.

Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers.

Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues.

Circulating molecular markers in pancreatic cancer: ready for clinical use?

Blood-based miRNAs as noninvasive diagnostic and surrogative biomarkers in colorectal cancer.

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts.

Distinct miRNA profiles are associated with malignant transformation of pancreatic cystic tumors revealing potential biomarkers for clinical use.

Circulating peripheral blood mononuclear cells exhibit altered miRNA expression patterns in pancreatic cancer.

The p53 miRNA interactome and its potential role in the cancer clinic.

Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN.

Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation.

MicroRNA-23b regulates cellular architecture and impairs motogenic and invasive phenotypes during cancer progression.

MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression.

Cell-free DNA for the detection of pancreatic, liver and upper gastrointestinal cancers: has progress been made?

A microRNA meta-signature for pancreatic ductal adenocarcinoma.

Reduced dissemination of circulating tumor cells with no-touch isolation surgical technique in patients with pancreatic cancer.

miR-15b and miR-17 Are Tumor-Derived Plasma MicroRNAs Dysregulated in Colorectal Neoplasia.

Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets.

Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer.

miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells.

5' isomiR variation is of functional and evolutionary importance.

Noncoding RNAs and the control of hormonal signaling via nuclear receptor regulation.

The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs.