Nadejda Sigal

3D model of the Escherichia coli multidrug transporter MdfA reveals an essential membrane-embedded positive charge.

No single irreplaceable acidic residues in the Escherichia coli secondary multidrug transporter MdfA.

Promiscuity in multidrug recognition and transport: the bacterial MFS Mdr transporters.

MdfA from Escherichia coli, a model protein for studying secondary multidrug transport.

E. coli multidrug transporter MdfA is a monomer.

The secondary multidrug/proton antiporter MdfA tolerates displacements of an essential negatively charged side chain.

Radical polymerization of the silene (Me3Si)2Si=CR2 by hydrogen transfer from a trimethylsilyl group.

Widespread remodeling of mid-coding sequence nucleosomes by Isw1.

Divergence of nucleosome positioning between two closely related yeast species: genetic basis and functional consequences.

Chromatin regulators as capacitors of interspecies variations in gene expression.

Manipulating the drug/proton antiport stoichiometry of the secondary multidrug transporter MdfA.

Prophage excision activates Listeria competence genes that promote phagosomal escape and virulence.

Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence.

Membrane chaperone SecDF plays a role in the secretion of Listeria monocytogenes major virulence factors.

Listeria monocytogenes multidrug resistance transporters and cyclic di-AMP, which contribute to type I interferon induction, play a role in cell wall stress.

Listeria monocytogenes MDR transporters are involved in LTA synthesis and triggering of innate immunity during infection.

Ribosomal mutations affecting the translation of genes that use non-optimal codons.

The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA.

The human P-glycoprotein transporter enhances the type I interferon response to Listeria monocytogenes infection.

A new perspective on lysogeny: prophages as active regulatory switches of bacteria.