Shamgar Ben-Eliyahu

The price of anticancer intervention. Does surgery promote metastasis?

The promotion of tumor metastasis by surgery and stress: immunological basis and implications for psychoneuroimmunology.

Prostaglandin e(2) suppresses NK activity in vivo and promotes postoperative tumor metastasis in rats.

Differences in number and activity of peripheral natural killer cells in primary versus secondary recurrent miscarriage.

Potential prophylactic measures against postoperative immunosuppression: could they reduce recurrence rates in oncological patients?

Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.

Indomethacin attenuates the immunosuppressive and tumor-promoting effects of surgery.

Effects of fentanyl on natural killer cell activity and on resistance to tumor metastasis in rats. Dose and timing study.

Marginating pulmonary-NK activity and resistance to experimental tumor metastasis: suppression by surgery and the prophylactic use of a beta-adrenergic antagonist and a prostaglandin synthesis inhibitor.

Poly I-C induces early embryo loss in f344 rats: a potential role for NK cells.

Autologous control of a highly malignant syngeneic CRNK-16 leukemia in the rat: a role for NK cells.

High NK cell activity in recurrent miscarriage: what are we really measuring?

Amelioration of operation-induced suppression of marginating pulmonary NK activity using poly IC: a potential approach to reduce postoperative metastasis.

Inducing a mode of NK-resistance to suppression by stress and surgery: a potential approach based on low dose of poly I-C to reduce postoperative cancer metastasis.

Immune suppression while awaiting surgery and following it: dissociations between plasma cytokine levels, their induced production, and NK cell cytotoxicity.

Prophylactic IL-12 treatment reduces postoperative metastasis: mediation by increased numbers but not cytotoxicity of NK cells.

Stress, NK cells, and cancer: Still a promissory note.

Male--female differences in the impact of beta-adrenoceptor stimulation on resistance to experimental metastasis: exploring the effects of age and gonadal hormone involvement.

Can regional analgesia reduce the risk of recurrence after breast cancer? Methodology of a multicenter randomized trial.

Perioperative use of beta-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis.

Metastatic-promoting effects of LPS: sexual dimorphism and mediation by catecholamines and prostaglandins.

Blood transfusion promotes cancer progression: a critical role for aged erythrocytes.

CpG-C oligodeoxynucleotides limit the deleterious effects of beta-adrenoceptor stimulation on NK cytotoxicity and metastatic dissemination.

Immune perturbations in patients along the perioperative period: alterations in cell surface markers and leukocyte subtypes before and after surgery.

The marginating-pulmonary immune compartment in rats: characteristics of continuous inflammation and activated NK cells.

Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor.

Synergism between immunostimulation and prevention of surgery-induced immune suppression: an approach to reduce post-operative tumor progression.

Effect of beta blocker combined with COX-2 inhibitor on colonic anastomosis in rats.

CpG-C immunotherapeutic efficacy is jeopardized by ongoing exposure to stress: potential implications for clinical use.

Continuous stress disrupts immunostimulatory effects of IL-12.

Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses.

Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity.

Stress and skin leukocyte trafficking as a dual-stage process.

Fish oil attenuates surgery-induced immunosuppression, limits post-operative metastatic dissemination and increases long-term recurrence-free survival in rodents inoculated with cancer cells.

Surgery and stress promote cancer metastasis: new outlooks on perioperative mediating mechanisms and immune involvement.

A new approach to reducing postsurgical cancer recurrence: perioperative targeting of catecholamines and prostaglandins.

Can we really know if a stressor increases or decreases natural killer cell activity?

Resilience of the immune system in healthy young students to 30-hour sleep deprivation with psychological stress.

The marginating-pulmonary immune compartment in mice exhibits increased NK cytotoxicity and unique cellular characteristics.

Impact of surgical extent and sex on the hepatic metastasis of colon cancer.

Surgery as a double-edged sword: a clinically feasible approach to overcome the metastasis-promoting effects of surgery by blunting stress and prostaglandin responses.

In vivo suppression of NK cell cytotoxicity by stress and surgery: glucocorticoids have a minor role compared to catecholamines and prostaglandins.

Plasma IL-12 levels are suppressed in vivo by stress and surgery through endogenous release of glucocorticoids and prostaglandins but not catecholamines or opioids.

The misleading nature of in vitro and ex vivo findings in studying the impact of stress hormones on NK cell cytotoxicity.

Exploiting the critical perioperative period to improve long-term cancer outcomes.

Perioperative treatment with the new synthetic TLR-4 agonist GLA-SE reduces cancer metastasis without adverse effects.

Reducing liver metastases of colon cancer in the context of extensive and minor surgeries through β-adrenoceptors blockade and COX2 inhibition.