Steven Dow

Strain-based genetic differences regulate the efficiency of systemic gene delivery as well as expression.

Enhancing antimelanoma immune responses through apoptosis.

Growth inhibition of an orthotopic glioblastoma in immunocompetent mice by cationic lipid-DNA complexes.

Use of immunostimulatory liposome-nucleic acid complexes in allergen-specific immunotherapy of dogs with refractory atopic dermatitis - a pilot study.

Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes.

Phase I study of liposome-DNA complexes encoding the interleukin-2 gene in dogs with osteosarcoma lung metastases.

Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.

Early interaction of Yersinia pestis with APCs in the lung.

Francisella tularensis induces aberrant activation of pulmonary dendritic cells.

Protective immunity against acute phleboviral infection elicited through immunostimulatory cationic liposome-DNA complexes.

Effects of chemotherapy on immune responses in dogs with cancer.

When the leader has a group in a difficult situation.

Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes.

Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes.

A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model.

Evaluation of a novel immunotherapy for treatment of chronic rhinitis in cats.

Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines.

Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs.

Evaluation of a novel tumor vaccine in dogs with hemangiosarcoma.

Sustained generation of tissue dendritic cells from cats using organ stromal cell cultures.

Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma.

Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs.

Neutrophil function in septic dogs.

Oxidative stress during acute FIV infection in cats.

Liposome-nucleic acid immunotherapeutics.

Immunoproteomic identification of bovine pericardium xenoantigens.

Prophylaxis with cationic liposome-DNA complexes protects hamsters from phleboviral disease: importance of liposomal delivery and CpG motifs.

Protection from pneumonic infection with burkholderia species by inhalational immunotherapy.

Lung environment determines unique phenotype of alveolar macrophages.

Mucosal immunotherapy for protection from pneumonic infection with Francisella tularensis.

Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.

Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses.

Evaluation of liposomal clodronate for treatment of malignant histiocytosis in dogs.

Molecular basis of rare aminoglycoside susceptibility and pathogenesis of Burkholderia pseudomallei clinical isolates from Thailand.

Type I interferons inhibit the generation of tumor-associated macrophages.

Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.

Immunotherapy markedly increases the effectiveness of antimicrobial therapy for treatment of Burkholderia pseudomallei infection.

Present and future therapeutic strategies for melioidosis and glanders.

Dietary selenium modulates activation and differentiation of CD4+ T cells in mice through a mechanism involving cellular free thiols.

How companion animals contribute to the fight against cancer in humans.

A Burkholderia pseudomallei deltapurM mutant is avirulent in immunocompetent and immunodeficient animals: candidate strain for exclusion from select-agent lists.

Serum concentrations of monocyte chemoattractant protein-1 in healthy and critically ill dogs.

Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures.

Protection against pneumonic plague following oral immunization with a non-replicating vaccine.

Minimally invasive assessment of tumor angiogenesis by fine needle aspiration and flow cytometry.

Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis.

Evaluation of intrarenal mesenchymal stem cell injection for treatment of chronic kidney disease in cats: a pilot study.

Mucosal immunization with liposome-nucleic acid adjuvants generates effective humoral and cellular immunity.

The Burkholderia pseudomallei Δasd mutant exhibits attenuated intracellular infectivity and imparts protection against acute inhalation melioidosis in mice.

MyD88-dependent recruitment of monocytes and dendritic cells required for protection from pulmonary Burkholderia mallei infection.

Consumption of Rice Bran Increases Mucosal Immunoglobulin A Concentrations and Numbers of Intestinal Lactobacillus spp.

In vitro comparison of feline bone marrow-derived and adipose tissue-derived mesenchymal stem cells.