Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo ImagingAlessandra Nardini 1,2,3, Behjat Sadat Kariman 4, Mario Marini 5, Conci Conci 1, Marco Grassi 1, Margaux Bouzin 5, Maddalena Collini 5, Roberto Osellame 2, Giulio Cerullo 4, Manuela Teresa Raimondi 1, Giuseppe Chirico 5, Rebeca Martínez Vázquez 2
1Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, 2Istituto di Fotonica e Nanotecnologie (IFN), Consiglio Nazionale delle Ricerche (CNR), 3Department of Experimental Medicine, Università del Salento, 4Department of Physics, Politecnico di Milano, 5Department of Physics, Università di Milano-Bicocca
This protocol describes the fabrication of an implantable integrated imaging window using 3D laser printing. The window consists of a system of microlenses coupled with micro-scaffolds. The method involves two-photon polymerization (2PP) of the biocompatible photoresist SZ2080 in a continuous sequence, optimizing manufacturing efficiency and alignment between the different components.
