How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification IndexMarie Schaer 1, Meritxell Bach Cuadra 2,3, Nick Schmansky 4, Bruce Fischl 4, Jean-Philippe Thiran 2, Stephan Eliez 1
1Department of Psychiatry, University of Geneva School of Medicine, 2Signal Processing Laboratory, École Polytechnique Fédérale de Lausanne, 3Department of Radiology, University Hospital Center and University of Lausanne, 4Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital
Measuring gyrification (cortical folding) at any age represents a window into early brain development. Hence, we previously developed an algorithm to measure local gyrification at thousands of points over the hemisphere1. In this paper, we detail the computation of this local gyrification index.
