Orthotopic Aortic Transplantation in Mice for the Study of Vascular DiseaseLingling Guo 1, Anupam Agarwal 2, James F. George 1
1Department of Surgery, The University of Alabama at Birmingham , 2Department of Medicine, The University of Alabama at Birmingham
We describe a technique in which a section of the abdominal aorta from a mouse is transplanted orthotopically to just below the renal arteries in an allogeneic or syngeneic recipient. This technique can be useful in studies in which transplantation of large arteries of uniform size is deemed advantageous.
