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Massachusetts General Hospital/Harvard Medical School

2 ARTICLES PUBLISHED IN JoVE

Medicine

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Xueli Zhang^1,2, Chaincy Kuo³, Anna Moore¹, Chongzhao Ran¹

¹Molecular Imaging Laboratory, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, ²Center for Drug Discovery, School of Pharmacy, China Pharmaceutical University, ³Perkin Elmer

In this video report, we show the application of Cerenkov Luminescence Imaging (CLI) for interscapular brown adipose tissue in mice under activated and depressed conditions.

Bioengineering

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

Keumyeon Kim¹, Haeshin Lee^1,2, Seonki Hong^2,3

¹The Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology (KAIST), ²Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), ³Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School

We describe the simplest protocol to prepare biodegradable medical glue that has an effective hemostatic ability. TAPE is a water-immiscible supramolecular aggregate prepared by mixing of tannic acid, a ubiquitous compound found in plants, and poly(ethylene) glycol, yielding a 2.5 times greater water-resistant adhesion compared with commercial fibrin glue.