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1 ARTICLES PUBLISHED IN JoVE

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Behavior

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
Liana Melo-Thomas 1,2, K.-Alexander Engelhardt 1, Uwe Thomas 3, Dirk Hoehl 3, Sascha Thomas 3, Markus Wöhr 1, Bjoern Werner 4, Frank Bremmer 4, Rainer K.W. Schwarting 1
1Behavioral Neuroscience, Experimental and Biological Psychology, Philipps-Universität Marburg, 2Behavioral Neurosciences Institute (INeC), 3Thomas RECORDING GmbH, 4Department of Neurophysics, Philipps-Universität Marburg

A wireless, bidirectional system for multi-channel neural recordings and stimulation in freely behaving rats is introduced. The system is light and compact, thus having minimal impact on the animal´s behavioral repertoire. Moreover, this bidirectional system provides a sophisticated tool to assess causal relationships between brain activation patterns and behavior.

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