A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental ChemicalsJingshu Chen *2, Lei Zhong *1, Jing Wu 1, Sui Ke 2, Benjamin Morpurgo 3, Andrei Golovko 3, Nengtai Ouyang 4, Yuxiang Sun 2, Shaodong Guo 2, Yanan Tian 1,2
1Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, Hunan Agriculture University, 2Texas A&M University, 3Texas A&M Institute for Genomic Medicine, 4Sun Yat-Sen Memorial Hospital
Here we present a protocol to isolate mouse pancreatic islet cells for screening the ROS inductions by the xenobiotics in order to identify the potential diabetogenic xenobiotic chemicals.
