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1 ARTICLES PUBLISHED IN JoVE

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Medicine

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Parvathi Menon 1,2, Steve Vucic 1,2
1Department of Neurology, Westmead Hospital, 2Sydney Medical School, University of Sydney, Australia

Dissociated atrophy of intrinsic hand muscles, termed the split hand, appears to be a specific feature of amyotrophic lateral sclerosis (ALS). Consequently, a novel neurodiagnostic test, termed the split hand index, was developed to quantify the clinical phenomenon of the split hand, which differentiated ALS from mimic disorders.

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