Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery SystemMatthew B Lawrenz 1,2, Ramy A. Fodah 2, Maria G. Gutierrez 2, Jonathan Warawa 1,2
1Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville Medical School, 2Department of Microbiology and Immunology, University of Louisville Medical School
Intubation-mediated intratracheal (IMIT) instillation of reagents is an excellent, noninvasive method for studying respiratory disease, as well as a method for instilling therapeutic reagents directly into the lung. It is a rapid and highly reproducible method which is suitable for preclinical testing.
