Describing a Transcription Factor Dependent Regulation of the MicroRNA TranscriptomeUri Rozovski 1, Inbal Hazan-Halevy 2, George Calin 3, David Harris 4, Ping Li 4, Zhiming Liu 4, Michael J. Keating 4, Zeev Estrov 4
1Division of Hematology, Davidoff Cancer Center, Rabin Medical Center, 2The Center of Nanoscience and Nanotechnology, Tel Aviv University, 3Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 4Department of Leukemia, The University of Texas MD Anderson Cancer Center
Herein we propose a strategy to study the effect of a transcription factor of interest on the microRNA transcriptome using publically available data, computational resources and high throughput data from microRNA arrays after transfecting cells with small hairpin (sh)RNA targeting a transcription factor of interest.
