Preparation of Formalin-fixed Paraffin-embedded Tissue Cores for both RNA and DNA ExtractionPalak G. Patel 1,2, Shamini Selvarajah 1,2, Suzanne Boursalie 1,2, Nathan E. How 1,2, Joshua Ejdelman 3, Karl-Philippe Guerard 3, John M. Bartlett 4, Jacques Lapointe 3, Paul C. Park 1, John B. A. Okello 1,2, David M. Berman 1,2
1Department of Pathology & Molecular Medicine, Queen's University, 2Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, 3Department of Surgery, Division of Urology, McGill University, 4Transformative Pathology Program, Ontario Institute for Cancer Research (OICR)
This modified extraction protocol improves RNA and DNA yields from more precisely targeted regions of interest in histopathologic tissue blocks.
