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Universität Leipzig

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
Jörg Schnauß *1,2, Martin Glaser *1,2, Jessica S. Lorenz 1, Carsten Schuldt 1,2, Christin Möser 1, Martin Sajfutdinow 1, Tina Händler 1,2, Josef A. Käs 2, David M. Smith 1
1Fraunhofer Institute for Cell Therapy and Immunology, 2Institute of Experimental Physics I, Universität Leipzig

Semiflexible polymers display unique mechanical properties that are extensively applied by living systems. However, systematic studies on biopolymers are limited since properties such as polymer rigidity are inaccessible. This manuscript describes how this limitation is circumvented by programmable DNA nanotubes, enabling experimental studies on the impact of filament rigidity.

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