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Lausanne University Hospital (CHUV)

1 ARTICLES PUBLISHED IN JoVE

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Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Jessica Lavier 1,2, Manon Beaumann 3, Steeve Ménetrey 3, Lucia Mazzolai 1, Anne-Christine Peyter 3, Maxime Pellegrin 1, Grégoire P. Millet 2
1Division of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), 2Institute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, 3Neonatal Research Laboratory, Clinic of Neonatology, Department Woman-Mother-Child, Lausanne University Hospital

High-intensity training in hypoxia is a protocol that has been proven to induce vascular adaptations potentially beneficial in some patients and to improve athletes' repeated sprint ability. Here, we test the feasibility of training mice using that protocol and identify those vascular adaptations using ex vivo vascular function assessment.

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