A Freeze-Thawing Method to Prepare Chitosan-Poly(vinyl alcohol) Hydrogels Without Crosslinking Agents and Diflunisal Release StudiesMaría Dolores Figueroa-Pizano 1, Itziar Vélaz 2, María Elisa Martínez-Barbosa 1
1Department of Polymers and Materials Research, University of Sonora, 2Department of Chemistry, Faculty of Sciences, University of Navarra
The freezing-thawing method is used to produce chitosan-poly(vinyl alcohol) hydrogels without crosslinking agents. For this method, it is important to consider the freezing conditions (temperature, number of cycles) and polymer ratio, which can affect the properties and applications of the obtained hydrogels.
