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A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Océane Blaise^*1,2, Constance Duchesne^*1,2, Sébastien Banzet², Antoine Rousseau¹, Nadira Frescaline^1,2

¹Laboratoire de Physique des Plasmas, École Polytechnique, Sorbonne Université, CNRS, ²Institut de Recherche Biomédicale des Armées, Clamart, INSERM UMRS-MD

The aim of this study was to develop a murine model of burn wound healing. A thermal burn was induced on the dorsal skin of mice using a preheated brass template. Burned tissue was debrided and overlaid with a skin graft harvested from the tail of a genetically similar donor mouse.