Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection FractionLuca Rosalia *1,2, Caglar Ozturk *1, Ellen T. Roche 1,2,3
1Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 2Health Science and Technology Program, Harvard/Massachusetts Institute of Technology, 3Department of Mechanical Engineering, Massachusetts Institute of Technology
This work introduces two computational models of heart failure with preserved ejection fraction based on a lumped-parameter approach and finite element analysis. These models are used to evaluate the changes in the hemodynamics of the left ventricle and related vasculature induced by pressure overload and diminished ventricular compliance.
