Labeling of Extracellular Vesicles for Monitoring Migration and Uptake in Cartilage ExplantsMaria Antònia Forteza-Genestra 1,2, Miquel Antich-Rosselló 1,2, Francisco Gabriel Ortega 1,2, Guillem Ramis-Munar 3, Javier Calvo 1,2,4, Antoni Gayà 1,2,4, Marta Monjo 1,2, Joana Maria Ramis 1,2
1Cell Therapy and Tissue Engineering Group, Research Institute on Health Sciences (IUNICS), University of the Balearic Islands, 2Health Research Institute of the Balearic Islands (IdISBa), 3Cellomics Unit, Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears, 4Fundació Banc de Sang i Teixits de les Illes Balears (FBSTIB)
Here, we present a protocol to label platelet lysate-derived extracellular vesicles to monitor their migration and uptake in cartilage explants used as a model for osteoarthritis.