Capítulo 24
Rotas Alternativas de Sinalização na Expressão Gênica
Via de Sinalização Notch
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands ...
Via de Sinalização Wnt Canônica
The gene encoding the main signaling molecules of the Wnt signaling pathways (the Wnt proteins) was discovered almost four decades ago by ...
Vias de Sinalização Wnt Não-canônicas
Wnt is a zygotic effect gene that is expressed during very early embryonic development. It regulates various processes in animals starting from early ...
Via de Sinalização Hedgehog
The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like ...
Via de sinalização dependente de NF-kB
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the ...
Ritmos Circadianos e Regulação Gênica
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and ...
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