10.9 : Matriz Óssea

Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals.Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can beobserved by an experiment: when the minerals of a bone are dissolved by soaking the bone in acid or vinegar, the result is a flexible, rubbery bone.

The calcification process begins with the crystallization of minerals in the microscopic spaces between the collagen fibers. These salt crystals form when calcium phosphate and calcium carbonate combine to create hydroxyapatite, which further incorporates other inorganic salts such as magnesium hydroxide, fluoride, and sulfate as it crystallizes, or calcifies, on the collagen fibers.

The bone matrix also acts as a reservoir for many physiologically important minerals, especially calcium and phosphorus. When required, the bone cellscalled osteoclasts, secrete enzymes and acids to break down the matrix and release these minerals back into the bloodstream to maintain optimal levels in the body. Calcium ions, for example, are essential for muscle contractions and controlling the flow of other ions involved in the transmission of nerve impulses; thus, it is essential to maintain the optimal concentration in the body.

This text is partially adapted from Openstax, Anatomy and Physiology 2e, Section 6.3: Bone Structure