Immunohistochemistry for Detection of the Locus Coeruleus in Brain Slices
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Results: Detection of Proteins Expressed in LC and Changes in Metal Homeostasis in Brain Sections
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Conclusion
Transcrição
Dysfunction of locus coeruleus has been implicated in neurological and neuropsychiatric disorders, including Parkinson disease, Alzheimer disease, depression, bipolar disorder, and anxiety. Given these roles, analysis of locus coeruleus is crucial
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The locus coeruleus is a small cluster of neurons involved in a variety of physiological processes. Here, we describe a protocol to prepare mouse brain sections for studies of proteins and metals in this nucleus.