Division of Rheumatology,
Allergy and Clinical Immunology,
Division of Rheumatology, Allergy and Clinical Immunology
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High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2012 | Pubmed ID: 22891353
A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.
Journal of medicinal chemistry Jun, 2013 | Pubmed ID: 23713581
Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.
PloS one , 2014 | Pubmed ID: 24498279
University of California, Davis
Dennis J. Wu1,
Neha Dixit1,
Erika Suzuki1,
Thanh Nguyen2,
Hyun Seock Shin1,
Jack Davis2,
Emanual Maverakis3,
Iannis E. Adamopoulos1,2
1Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis,
2Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children - Northern California,
3Department of Dermatology, University of California, Davis
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