Benjamin D. Ortiz

Factors binding a non-classical Cis-element prevent heterochromatin effects on locus control region activity.

The TCRalpha locus control region specifies thymic, but not peripheral, patterns of TCRalpha gene expression.

CTCF-independent, but not CTCF-dependent, elements significantly contribute to TCR-alpha locus control region activity.

A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.

Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once.

A role for autophagic protein beclin 1 early in lymphocyte development.

Complete TCR-α gene locus control region activity in T cells derived in vitro from embryonic stem cells.

Adapting in vitro embryonic stem cell differentiation to the study of locus control regions.