Srikanth Kudithipudi

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays.

Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase.

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9.

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails.

A fluorescence-based supramolecular tandem assay for monitoring lysine methyltransferase activity in homogeneous solution.

The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues.

Non-radioactive protein lysine methyltransferase microplate assay based on reading domains.

The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

Role of somatic cancer mutations in human protein lysine methyltransferases.

Application of histone modification-specific interaction domains as an alternative to antibodies.